Effectiveness of Posaconazole in Recalcitrant Fungal Keratitis Resistant to Conventional Antifungal Drugs
المؤلفون المشاركون
Altun, Ahmet
Olcaysu, Osman Okan
Altun, G.
Simsek, M. H.
Aki, S. F.
Kurna, S. A.
Sengor, T.
المصدر
Case Reports in Ophthalmological Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-11
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Purpose.
To present the success of posaconazole in two cases with recalcitrant fugal keratitis that were resistant to conventional antifungal drugs.
Method.
We presented two cases that were treated with posaconazole after the failure of fluconazole or voriconazole, amphotericin B, and natamycin therapy.
Case 1 was a 62-year-old man with a history of ocular trauma.
He had been using topical fluorometholone and tobramycin.
His best corrected visual acuity (BCVA) was hand motion.
He had 5.0 × 4.5 mm area of deep corneal ulcer with stromal infiltration.
Case 2 was a 14-year-old contact lens user.
He had been using topical moxifloxacin, tobramycin, and cyclopentolate.
His BCVA was 20/200.
He had a 4.0 × 3.0 mm area of pericentral corneal ulcer with deep corneal stromal infiltration and 2 mm hypopyon.
Results.
Both patients initially received systemic and topical fluconazole or voriconazole and amphotericin B and topical natamycin that were all ineffective.
But the response of posaconazole was significant.
After posaconazole, progressive improvement was seen in clinical appearance.
BCVA improved to 20/100 in case 1 and 20/40 in case 2.
Conclusion.
Posaconazole might be an effective treatment option for recalcitrant fusarium keratitis and/or endophthalmitis resistant to conventional antifungal drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Altun, Ahmet& Kurna, S. A.& Sengor, T.& Altun, G.& Olcaysu, Osman Okan& Aki, S. F.…[et al.]. 2014. Effectiveness of Posaconazole in Recalcitrant Fungal Keratitis Resistant to Conventional Antifungal Drugs. Case Reports in Ophthalmological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-491644
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Altun, Ahmet…[et al.]. Effectiveness of Posaconazole in Recalcitrant Fungal Keratitis Resistant to Conventional Antifungal Drugs. Case Reports in Ophthalmological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-491644
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Altun, Ahmet& Kurna, S. A.& Sengor, T.& Altun, G.& Olcaysu, Osman Okan& Aki, S. F.…[et al.]. Effectiveness of Posaconazole in Recalcitrant Fungal Keratitis Resistant to Conventional Antifungal Drugs. Case Reports in Ophthalmological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-491644
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491644
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر