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Characterization of Genipin-Modified Dentin Collagen
المؤلفون المشاركون
Burton, Andrew
Nagaoka, Hideaki
Miguez, Patricia A.
Yamauchi, Mitsuo
Ritter, André V.
Nagaoka, Hiroko
Walter, Ricardo
Boushell, Lee W.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-25
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Application of biomodification techniques to dentin can improve its biochemical and biomechanical properties.
Several collagen cross-linking agents have been reported to strengthen the mechanical properties of dentin.
However, the characteristics of collagen that has undergone agent-induced biomodification are not well understood.
The objective of this study was to analyze the effects of a natural cross-linking agent, genipin (GE), on dentin discoloration, collagen stability, and changes in amino acid composition and lysyl oxidase mediated natural collagen cross-links.
Dentin collagen obtained from extracted bovine teeth was treated with three different concentrations of GE (0.01%, 0.1%, and 0.5%) for several treatment times (0–24 h).
Changes in biochemical properties of NaB3H4-reduced collagen were characterized by amino acid and cross-link analyses.
The treatment of dentin collagen with GE resulted in a concentration- and time-dependent pigmentation and stability against bacterial collagenase.
The lysyl oxidase-mediated trivalent mature cross-link, pyridinoline, showed no difference among all groups while the major divalent immature cross-link, dehydro-dihydroxylysinonorleucine/its ketoamine in collagen treated with 0.5% GE for 24 h, significantly decreased compared to control (P< 0.05).
The newly formed GE-induced cross-links most likely involve lysine and hydroxylysine residues of collagen in a concentration-dependent manner.
Some of these cross-links appear to be reducible and stabilized with NaB3H4.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nagaoka, Hiroko& Nagaoka, Hideaki& Walter, Ricardo& Boushell, Lee W.& Miguez, Patricia A.& Burton, Andrew…[et al.]. 2014. Characterization of Genipin-Modified Dentin Collagen. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-491758
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nagaoka, Hiroko…[et al.]. Characterization of Genipin-Modified Dentin Collagen. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-491758
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nagaoka, Hiroko& Nagaoka, Hideaki& Walter, Ricardo& Boushell, Lee W.& Miguez, Patricia A.& Burton, Andrew…[et al.]. Characterization of Genipin-Modified Dentin Collagen. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-491758
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491758
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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