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Multiple Molecular and Cellular Mechanisms of Action of Lycopene in Cancer Inhibition
المؤلفون المشاركون
Sotelo, Julio
Cruz-Salgado, Arturo
Trejo-Solís, Cristina
Serrano-García, Norma
Torres-Ramos, Mónica
Pedraza-Chaverri, José
Jiménez-Farfán, Dolores
Osorio-Rico, Laura
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-21
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Epidemiological studies suggest that including fruits, vegetables, and whole grains in regular dietary intake might prevent and reverse cellular carcinogenesis, reducing the incidence of primary tumours.
Bioactive components present in food can simultaneously modulate more than one carcinogenic process, including cancer metabolism, hormonal balance, transcriptional activity, cell-cycle control, apoptosis, inflammation, angiogenesis and metastasis.
Some studies have shown an inverse correlation between a diet rich in fruits, vegetables, and carotenoids and a low incidence of different types of cancer.
Lycopene, the predominant carotenoid found in tomatoes, exhibits a high antioxidant capacity and has been shown to prevent cancer, as evidenced by clinical trials and studies in cell culture and animal models.
In vitro studies have shown that lycopene treatment can selectively arrest cell growth and induce apoptosis in cancer cells without affecting normal cells.
In vivo studies have revealed that lycopene treatment inhibits tumour growth in the liver, lung, prostate, breast, and colon.
Clinical studies have shown that lycopene protects against prostate cancer.
One of the main challenges in cancer prevention is the integration of new molecular findings into clinical practice.
Thus, the identification of molecular biomarkers associated with lycopene levels is essential for improving our understanding of the mechanisms underlying its antineoplastic activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Trejo-Solís, Cristina& Pedraza-Chaverri, José& Torres-Ramos, Mónica& Jiménez-Farfán, Dolores& Cruz-Salgado, Arturo& Serrano-García, Norma…[et al.]. 2013. Multiple Molecular and Cellular Mechanisms of Action of Lycopene in Cancer Inhibition. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-491982
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Trejo-Solís, Cristina…[et al.]. Multiple Molecular and Cellular Mechanisms of Action of Lycopene in Cancer Inhibition. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-17.
https://search.emarefa.net/detail/BIM-491982
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Trejo-Solís, Cristina& Pedraza-Chaverri, José& Torres-Ramos, Mónica& Jiménez-Farfán, Dolores& Cruz-Salgado, Arturo& Serrano-García, Norma…[et al.]. Multiple Molecular and Cellular Mechanisms of Action of Lycopene in Cancer Inhibition. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-491982
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491982
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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