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Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.
المؤلفون المشاركون
Sirmagul, Basar
Atli, Ozlem
Perk, Basak Ozlem
Duymus, Hale Gamze
Ilgin, Sinem
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-28
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The fruit of Physalis peruviana L.
(PPL) has been traditionally used as antispasmodic, diuretic, antiseptic, sedative, and analgesic all over the world.
We aimed to perform qualitative content analysis of the fruits of PPL and to clarify the in vitro genotoxicity and in vivo acute and subchronic toxicity of the fruit.
Lyophilized fruit juice does not induce genetic damage.
In the acute toxicity studies, LD50 value of the fruit was found to be more than 5000 mg kg−1 for both sexes.
According to the subchronic toxicity studies, hepatic, renal, and hematological toxic effects were not induced in both sexes.
Plasma troponin I (only in the group treated with 5000 mg kg−1 of lyophilized fruit juice) and troponin T levels were significantly increased in male groups treated with lyophilized fruit juice compared to the control group.
Furthermore, potassium level was significantly increased in the male group treated with 5000 mg kg−1 of lyophilized fruit juice.
These findings were considered to indicate the myocardial damage particularly in the male group treated with 5000 mg kg−1 of lyophilized fruit juice.
In conclusion, lyophilized fruit juice of PPL is shown to induce cardiac toxicity only at high doses and in male gender.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Perk, Basak Ozlem& Ilgin, Sinem& Atli, Ozlem& Duymus, Hale Gamze& Sirmagul, Basar. 2013. Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-492162
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Perk, Basak Ozlem…[et al.]. Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-492162
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Perk, Basak Ozlem& Ilgin, Sinem& Atli, Ozlem& Duymus, Hale Gamze& Sirmagul, Basar. Acute and Subchronic Toxic Effects of the Fruits of Physalis peruviana L.. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-492162
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-492162
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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