Outcome of Very Late Relapse in Patients with Hodgkin's Lymphomas
المؤلفون المشاركون
Pastore, Domenico
Giordano, Annamaria
Perrone, Tommasina
Liso, Vincenzo
Spina, Alessandro
Gaudio, Francesco
de' Risi, Clara
Specchia, Giorgina
Pavone, Vincenzo
Delia, Mario
Curci, Paola
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-12-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Recurrences of Hodgkin's Lymphoma (HL) 5 years after the initial therapy are rare.
The aim of this study is to report a single centre experience of the clinical characteristics, outcome, and toxicity of pts who experienced very late relapses, defined as relapses that occurred 5 or more years after the achievement of first complete remission.
Of 532 consecutive pts with classical HL treated at our Institute from 1985 to 1999, 452 pts (85%) achieved a complete remission.
Relapse occurred in 151 pts: 135 (29.8%) within 5 years and 16 over 5 years (3.5%, very late relapses).
Very late relapses occurred after a median disease-free interval of 7 years (range: 5–18).
Salvage treatment induced complete remission in 14 pts (87.5%).
At a median of 4 years after therapy for very late relapse, 10 pts (63%) are still alive and free of disease and 6 (37%) died (1 from progressive HL, 1 from cardiac disease, 1 from thromboembolic disease, 1 from HCV reactivation, and 2 from bacterial infection).
The probability of failure-free survival at 5 years was 75%.
The majority of deaths are due to treatment-related complications.
Therapy regimens for very late relapse HL are warranted to minimize complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gaudio, Francesco& Giordano, Annamaria& Pavone, Vincenzo& Perrone, Tommasina& Curci, Paola& Pastore, Domenico…[et al.]. 2010. Outcome of Very Late Relapse in Patients with Hodgkin's Lymphomas. Advances in Hematology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-492187
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gaudio, Francesco…[et al.]. Outcome of Very Late Relapse in Patients with Hodgkin's Lymphomas. Advances in Hematology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-492187
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gaudio, Francesco& Giordano, Annamaria& Pavone, Vincenzo& Perrone, Tommasina& Curci, Paola& Pastore, Domenico…[et al.]. Outcome of Very Late Relapse in Patients with Hodgkin's Lymphomas. Advances in Hematology. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-492187
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-492187
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر