Activity of Cathelicidin Peptides against Simkania negevensis

الملخص EN

The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated.

Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL.

In comparison to chlamydiae, S.

negevensis proved to be more susceptible to the antimicrobial peptides tested.