Correctness of Protein Identifications of Bacillus subtilis Proteome with the Indication on Potential False Positive Peptides Supported by Predictions of Their Retention Times
المؤلفون المشاركون
Obuchowski, Michał
Grzenkowicz-Wydra, Jolanta
Bączek, Tomasz
Massolini, Gabriella
Temporini, Caterina
Kaliszan, Roman
Macur, Katarzyna
Corana, Federica
المصدر
Journal of Biomedicine and Biotechnology
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2009-12-23
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The predictive capability of the retention time prediction model based on quantitative structure-retention relationships (QSRR) was tested.
QSRR model was derived with the use of set of peptides identified with the highest scores and originated from 8 known proteins annotated as model ones.
The predictive ability of the QSRR model was verified with the use of a Bacillus subtilis proteome digest after separation and identification of the peptides by LC-ESI-MS/MS.
That ability was tested with three sets of testing peptides assigned to the proteins identified with different levels of confidence.
First, the set of peptides identified with the highest scores achieved in the search were considered.
Hence, proteins identified on the basis of more than one peptide were taken into account.
Furthermore, proteins identified on the basis of just one peptide were also considered and, depending on the possessed scores, both above and below the assumed threshold, were analyzed in two separated sets.
The QSRR approach was applied as the additional constraint in proteomic research verifying results of MS/MS ion search and confirming the correctness of the peptides identifications along with the indication of the potential false positives.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Macur, Katarzyna& Bączek, Tomasz& Kaliszan, Roman& Temporini, Caterina& Corana, Federica& Massolini, Gabriella…[et al.]. 2009. Correctness of Protein Identifications of Bacillus subtilis Proteome with the Indication on Potential False Positive Peptides Supported by Predictions of Their Retention Times. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-493038
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Macur, Katarzyna…[et al.]. Correctness of Protein Identifications of Bacillus subtilis Proteome with the Indication on Potential False Positive Peptides Supported by Predictions of Their Retention Times. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-13.
https://search.emarefa.net/detail/BIM-493038
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Macur, Katarzyna& Bączek, Tomasz& Kaliszan, Roman& Temporini, Caterina& Corana, Federica& Massolini, Gabriella…[et al.]. Correctness of Protein Identifications of Bacillus subtilis Proteome with the Indication on Potential False Positive Peptides Supported by Predictions of Their Retention Times. Journal of Biomedicine and Biotechnology. 2009. Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-493038
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493038
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر