Different Apathy Profile in Behavioral Variant of Frontotemporal Dementia and Alzheimer's Disease : A Preliminary Investigation
المؤلفون المشاركون
Quaranta, Davide
Masullo, Carlo
Gainotti, Guido
Rossi, Concettina
Marra, Camillo
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Apathy is one of the most common behavioral symptoms of dementia; it is one of the salient features of behavioral variant of frontotemporal dementia (bvFTD) but is also very frequent in Alzheimer's disease.
This preliminary investigation was aimed at assessing the type of apathy-related symptoms in a population of bvFTD and AD subjects showing comparable apathy severity.
Each patient underwent a comprehensive neuropsychological assessment; behavioral changes were investigated by the neuropsychiatric inventory (NPI), using the NPI-apathy subscale to detect apathetic symptoms.
At univariate analysis, bvFTD subjects showed lack of initiation (χ2=4.602, p=0.032), reduced emotional output (χ2=6.493, p=0.008), and reduced interest toward friends and family members (χ2=4.898, p=0.027), more frequently than AD subjects.
BvFTD displayed higher scores than AD on NPI total score (p=0.005) and on subscales assessing agitation (p=0.004), disinhibition (p=0.007) and sleep disturbances (p=0.025); conversely, AD subjects were more impaired on memory, constructional abilities, and attention.
On multivariate logistic regression, reduced emotional output was highly predictive of bvFTD (OR=18.266; p=0.008).
Our preliminary findings support the hypothesis that apathy is a complex phenomenon, whose clinical expression is conditioned by the site of anatomical damage.
Furthermore, apathy profile may help in differentiating bvFTD from AD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Quaranta, Davide& Marra, Camillo& Rossi, Concettina& Gainotti, Guido& Masullo, Carlo. 2012. Different Apathy Profile in Behavioral Variant of Frontotemporal Dementia and Alzheimer's Disease : A Preliminary Investigation. Current Gerontology and Geriatrics Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493149
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Quaranta, Davide…[et al.]. Different Apathy Profile in Behavioral Variant of Frontotemporal Dementia and Alzheimer's Disease : A Preliminary Investigation. Current Gerontology and Geriatrics Research No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-493149
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Quaranta, Davide& Marra, Camillo& Rossi, Concettina& Gainotti, Guido& Masullo, Carlo. Different Apathy Profile in Behavioral Variant of Frontotemporal Dementia and Alzheimer's Disease : A Preliminary Investigation. Current Gerontology and Geriatrics Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493149
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493149
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر