Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts
المؤلفون المشاركون
Kazemi, Masoud
Nahrevanian, Shahab
Nahrevanian, Hossein
Soleymani Mashhadi, Soudeh
Eshaq Hosseini, Seyed Mahmood
Sheykhkanlooye Milan, Bayram
المصدر
Malaria Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo.
This is the first application of A.
sieberi for treatment of murine malaria.
A.
sieberi were collected at flowering stage from the Khorassan and Semnan provinces of Iran; the aerial parts were air-dried at room temperature and then powdered.
The powder was macerated in methanol, filtered with Bokhner hopper and solvent was separated in rotary evaporator.
Total herbal extract was subsequently processed for ether and chloroform extracts preparation.
The toxicity of herbal extract was assessed on naive NMRI mice with high, average and low doses; then pathophysiological signs were assessed.
Finally, the antimalarial efficacy was investigated on two groups of Plasmodium berghei infected mice.
Percentage of parasitaemia and pathophysiology were also evaluated.
The results of this assessment showed no toxicity even by high concentration of herbal extract.
A significant reduction in percentage of parasitaemia was observed; no alterations of hepatosplenomegaly and body weight were indicated in study group.
A.
sieberi extracts showed antimalarial effects against murine malaria with some efficacies on reducing pathophysiology.
However, there is requirement to find the major component of this herbal extract by further studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nahrevanian, Hossein& Sheykhkanlooye Milan, Bayram& Kazemi, Masoud& Eshaq Hosseini, Seyed Mahmood& Soleymani Mashhadi, Soudeh& Nahrevanian, Shahab. 2012. Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts. Malaria Research and Treatment،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493809
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nahrevanian, Hossein…[et al.]. Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts. Malaria Research and Treatment No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-493809
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nahrevanian, Hossein& Sheykhkanlooye Milan, Bayram& Kazemi, Masoud& Eshaq Hosseini, Seyed Mahmood& Soleymani Mashhadi, Soudeh& Nahrevanian, Shahab. Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts. Malaria Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-493809
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493809
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر