The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals
المؤلفون المشاركون
Ballantyne, Christie M.
Jones, Peter H.
Vrablik, Michal
Hoogeveen, Ron C.
Sun, Wensheng
Tumova, Eva
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-19
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective.
Obesity is linked with a state of increased oxidative stress, which plays an important role in the etiology of atherosclerosis and type 2 diabetes mellitus.
The aim of our study was to evaluate the effect of rapid weight loss on oxidative stress markers in obese individuals with metabolic syndrome (MetS).
Design and Methods.
We measured oxidative stress markers in 40 obese subjects with metabolic syndrome (MetS+), 40 obese subjects without metabolic syndrome (MetS−), and 20 lean controls (LC) at baseline and after three months of very low caloric diet.
Results.
Oxidized low density lipoprotein (ox-LDL) levels decreased by 12% in MetS+ subjects, associated with a reduction in total cholesterol (TC), even after adjustment for age and sex.
Lipoprotein associated phospholipase A2 (Lp-PLA2) activity decreased by 4.7% in MetS+ subjects, associated with a drop in LDL-cholesterol (LDL-C), TC, and insulin levels.
Multivariate logistic regression analysis showed that a model including ox-LDL, LpPLA2 activity, and myeloperoxidase (MPO) improved prediction of MetS status among obese individuals compared to each oxidative stress marker alone.
Conclusions.
Oxidative stress markers were predictive of MetS in obese subjects, suggesting a higher oxidative stress.
Rapid weight loss resulted in a decline in oxidative stress markers, especially in MetS+ patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tumova, Eva& Sun, Wensheng& Jones, Peter H.& Vrablik, Michal& Ballantyne, Christie M.& Hoogeveen, Ron C.. 2013. The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals. Journal of Obesity،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-494033
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tumova, Eva…[et al.]. The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals. Journal of Obesity No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-494033
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tumova, Eva& Sun, Wensheng& Jones, Peter H.& Vrablik, Michal& Ballantyne, Christie M.& Hoogeveen, Ron C.. The Impact of Rapid Weight Loss on Oxidative Stress Markers and the Expression of the Metabolic Syndrome in Obese Individuals. Journal of Obesity. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-494033
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494033
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر