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Etiology and Outcome of Patients with HIV Infection and Respiratory Failure Admitted to the Intensive Care Unit
المؤلفون المشاركون
Llosa, Alfonso
Flores, Rosemarie
Tran, Truc
Fishkin, Edward
Ahmad, Noeen
Orsini, Jose
Butala, Ashvin
المصدر
Interdisciplinary Perspectives on Infectious Diseases
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-28
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Although access to HAART has prolonged survival and improved quality of life, HIV-infected patients with severe immunosuppression or comorbidities may develop complications that require critical care support.
Our objective is to evaluate the etiology of respiratory failure in patients with HIV infection admitted to the ICU, its relationship with the T-lymphocytes cell count as well as the use of HAART, and its impact on outcome.
Methods.
A single-center, prospective, and observational study among all patients with HIV-infection and respiratory failure admitted to the ICU from December 1, 2011, to February 28, 2013, was conducted.
Results.
A total of 42 patients were admitted during the study period.
Their median CD4 cell count was 123 cells/μL (mean 205.7, range 2.0–694.0), with a median HIV viral load of 203.5 copies/mL (mean 58,676, range <20–367,649).
At the time of admission, 23 patients (54.8%) were receiving HAART.
Use of antiretroviral therapy at ICU admission was not associated with survival, but it was associated with higher CD4 cell counts and lower HIV viral loads.
Twenty-five patients (59.5%) had respiratory failure secondary to non-HIV-related diseases.
Mechanical ventilation was required in 36 patients (85.1%).
Thirteen patients (31.0%) died.
Conclusions.
Noninfectious etiologies of respiratory failure account for majority of HIV-infected patients admitted to ICU.
Increased mortality was observed among patients with sepsis as etiology of respiratory failure (HIV related and non-AIDS related), in those receiving mechanical ventilation, and in patients with decreased CD4 cell count.
Survival was not associated with the use of HAART.
Complementary studies are warranted to address the impact of HAART on outcomes of HIV-infected patients with respiratory failure admitted to ICU.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Orsini, Jose& Ahmad, Noeen& Butala, Ashvin& Flores, Rosemarie& Tran, Truc& Llosa, Alfonso…[et al.]. 2013. Etiology and Outcome of Patients with HIV Infection and Respiratory Failure Admitted to the Intensive Care Unit. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-494300
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Orsini, Jose…[et al.]. Etiology and Outcome of Patients with HIV Infection and Respiratory Failure Admitted to the Intensive Care Unit. Interdisciplinary Perspectives on Infectious Diseases No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-494300
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Orsini, Jose& Ahmad, Noeen& Butala, Ashvin& Flores, Rosemarie& Tran, Truc& Llosa, Alfonso…[et al.]. Etiology and Outcome of Patients with HIV Infection and Respiratory Failure Admitted to the Intensive Care Unit. Interdisciplinary Perspectives on Infectious Diseases. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-494300
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494300
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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