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Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia
المؤلفون المشاركون
Schretlen, David
Adali, Tülay
Calhoun, Vince D.
Xu, Lai
Pearlson, Godfrey
المصدر
Neurology Research International
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-10-10
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
We present a feature extraction method to emphasize the interrelationship between gray and white matter and identify tissue distribution abnormalities in schizophrenia.
This approach utilizes novel features called structural phase and magnitude images.
The phase image indicates the relative contribution of gray and white matter, and the magnitude image reflects the overall tissue concentration.
Three different analyses are applied to the phase and magnitude images obtained from 120 healthy controls and 120 schizophrenia patients.
First, a single-subject subtraction analysis is computed for an initial evaluation.
Second, we analyze the extracted features using voxel based morphometry (VBM) to detect voxelwise group differences.
Third, source based morphometry (SBM) analysis was used to determine abnormalities in structural networks that co-vary in a similar way.
Six networks were identified showing significantly lower white-to-gray matter in schizophrenia, including thalamus, right precentral-postcentral, left pre/post-central, parietal, right cuneus-frontal, and left cuneus-frontal sources.
Interestingly, some networks look similar to functional patterns, such as sensory-motor and vision.
Our findings demonstrate that structural phase and magnitude images can naturally and efficiently summarize the associated relationship between gray and white matter.
Our approach has wide applicability for studying tissue distribution differences in the healthy and diseased brain.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Lai& Adali, Tülay& Schretlen, David& Pearlson, Godfrey& Calhoun, Vince D.. 2011. Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia. Neurology Research International،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-494473
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Lai…[et al.]. Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia. Neurology Research International No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-494473
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Lai& Adali, Tülay& Schretlen, David& Pearlson, Godfrey& Calhoun, Vince D.. Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia. Neurology Research International. 2011. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-494473
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494473
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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