Animal Experimental Study of the Fully Biodegradable Atrial Septal Defect (ASD) Occluder
المؤلفون المشاركون
Li, Zhao-feng
Huang, Xin-miao
Jiang, Hai-bing
Wang, Wei
Hu, Jian-qiang
Zhao, Xian-xian
Bai, Yuan
Zhu, Yu-feng
Qin, Yong-wen
Chen, Ying
Cao, Jiang
المصدر
Journal of Biomedicine and Biotechnology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study was conducted to evaluate the feasibility, safety, biocompatibility, and degradation features of a fully biodegradable occluder for closure of atrial septal defect (ASD) in an acute canine model.
The ASD was created in 20 healthy mongrel dogs by the brockenbrough needle, and the fully biodegradable occluders were implanted by self-made delivery system.
The success rate and complications were observed.
Acute ASD models were successfully created in 18 dogs, and 16 occluders were successfully implanted in the ASD models.
Animals were sacrificed at different times after procedure.
The cardiac gross anatomy showed that all occluders were stable in the interatrial septum, no vegetation or thrombus formation was observed on the surface of all occluders.
They were embedded into endogenous host tissue gradually at 12-week follow-up.
Different periods of pathological observations suggested that the occluders degraded gradually over about 24 weeks and essentially became an integral part of the septum.
Transcatheter closure of ASD in acute canine model using the fully biodegradable ASD occluder has the potential of a high successful rate of technique, excellent biocompatibility, and fewer complications with adequate, immediate, and short-term results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Yu-feng& Huang, Xin-miao& Cao, Jiang& Hu, Jian-qiang& Bai, Yuan& Jiang, Hai-bing…[et al.]. 2012. Animal Experimental Study of the Fully Biodegradable Atrial Septal Defect (ASD) Occluder. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-494558
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Yu-feng…[et al.]. Animal Experimental Study of the Fully Biodegradable Atrial Septal Defect (ASD) Occluder. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-494558
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Yu-feng& Huang, Xin-miao& Cao, Jiang& Hu, Jian-qiang& Bai, Yuan& Jiang, Hai-bing…[et al.]. Animal Experimental Study of the Fully Biodegradable Atrial Septal Defect (ASD) Occluder. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-494558
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494558
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر