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Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia
المؤلفون المشاركون
El Omri, Abdelfatteh
Isoda, Hiroko
Han, Junkyu
Ben Othman, Mahmoud
Ksouri, Riadh
Neffati, Mohamed
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study aimed to investigate the antistress properties of the ethanol extract of Cymbopogon schoenanthus (CSEE), growing wild in the southern part of Tunisia.
The effect of extracts on H2O2-induced cytotoxicity and stress in human neuroblastoma SH-SY5Y cells.
Its effect on stress-induced in ICR mice was exposed to force swim and tail suspension, in concordance with heat shock protein expression (HSP27 and HSP90), corticosterone, and catecholamine neurotransmitters level.
Our results demonstrated that pretreatment of SH-SY5Y cells with CSEE at 1/2000, 1/1000, and 1/500 v/v dilutions significantly inversed H2O2-induced neurotoxicity.
Moreover, CSEE treatments significantly reversed heat shock protein expression in heat-stressed HSP47-transformed cells (42°C, for 90 min) and mRNA expression of HSP27 and HSP90 in H2O2-treated SH-SY5Y.
Daily oral administration of 100 mg/kg and 200 mg/kg CSEE was conducted to ICR mice for 2 weeks.
It was resulted in a significant decrease of immobility time in forced swimming and tail suspension tests.
The effect of CSEE on animal behavior was concordant with a significant regulation of blood serum corticosterone and cerebral cortex levels of catecholamine (dopamine, adrenaline, and noradrenaline).
Therefore, this study was attempted to demonstrate the preventive potential of CSEE against stress disorders at in vitro and in vivo levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ben Othman, Mahmoud& Han, Junkyu& El Omri, Abdelfatteh& Ksouri, Riadh& Neffati, Mohamed& Isoda, Hiroko. 2013. Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-494681
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ben Othman, Mahmoud…[et al.]. Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-494681
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ben Othman, Mahmoud& Han, Junkyu& El Omri, Abdelfatteh& Ksouri, Riadh& Neffati, Mohamed& Isoda, Hiroko. Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-494681
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494681
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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