![](/images/graphics-bg.png)
The Renal Effects of Vanadate Exposure : Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies
المؤلفون المشاركون
Fornal, Emilia
Niedźwiecka, Irmina
Gołębiowska, Dorota
Adamczyk, Agnieszka
Ścibior, Agnieszka
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-28
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
The alterations in the levels/activities of selected biomarkers for detecting kidney toxicity and in the levels of some oxidative stress (OS) markers and elements were studied in male rats to evaluate biochemically the degree of kidney damage, investigate the role of OS in the mechanism of functional renal disorders, reveal potential biomarkers of renal function, and assess the renal mineral changes in the conditions of a 12-week sodium metavanadate (SMV, 0.125 mg V/mL) exposure.
The results showed that OS is involved in the mechanism underlying the development of SMV-induced functional renal disturbances.
They also suggest that the urinary cystatin C (CysCu) and kidney injury molecule-1 (KIM-1u) could be the most appropriate to evaluate renal function at the conditions of SMV intoxication when the fluid intake, excreted urinary volume (EUV), body weight (BW), and the urinary creatinine excretion (Creu) decreased.
The use of such tests as the urinary lactate dehydrogenase, alkaline phosphatase, γ-glutamyltranspeptidase, and N-acetyl-β-D-glucosaminidase (LDHu, ALPu, GGTPu, and NAGu) seems not to be valid given their reduced activities.
The use of only traditional biomarkers of renal function in these conditions may, in turn, be insufficient because their alterations are greatly influenced by the changes in the fluid intake and/or BW.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ścibior, Agnieszka& Gołębiowska, Dorota& Adamczyk, Agnieszka& Niedźwiecka, Irmina& Fornal, Emilia. 2014. The Renal Effects of Vanadate Exposure : Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies. BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-494898
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ścibior, Agnieszka…[et al.]. The Renal Effects of Vanadate Exposure : Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies. BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-494898
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ścibior, Agnieszka& Gołębiowska, Dorota& Adamczyk, Agnieszka& Niedźwiecka, Irmina& Fornal, Emilia. The Renal Effects of Vanadate Exposure : Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-494898
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-494898
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)