Superficial Siderosis and Anticoagulation Therapy : Different Presentations, Different Outcomes
المؤلفون المشاركون
Coutinho, Paula
Ruano, Luís
Barreto, Rui Duarte
Veira, Carlos
Cruz, Vítor Tedim
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Superficial siderosis is a potentially manageable neurodegenerative disorder, caused by chronic subarachnoid haemorrhage and iron deposition along the central nervous system surfaces.
Association with oral anticoagulant therapy is well known, but its definite role as a causative agent is yet to be clarified.
Two Caucasian women, both under long-term oral anticoagulation: a 74 year old woman with slowly progressive hearing loss and mild cerebellar ataxia; a 72 year old woman suffering from behavioural changes, rapidly progressive cognitive decline and latter developing paraparesis.
Magnetic resonance imaging showed striking hypointensities along the surfaces of cerebellum, brainstem, frontotemporal cortices, spinal cord, and lumbar arachnoid therefore suggesting superficial siderosis.
No specific bleeding source was found in any of the patients.
Anticoagulation could not be stopped in the first patient due to a mechanic valve and slowly progressive worsening occurred.
In contrast, for the second patient anticoagulation withdrawal was feasible and marked motor and cognitive improvement ensued.
Superficial siderosis is associated with unvarying progression, mostly when no direct source of bleeding is identified.
Nonetheless, we verified striking motor and cognitive improvement after anticoagulants withdrawal in one of the patients.
This may reinforce the need to consider such modifiable factor in future patient management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Barreto, Rui Duarte& Ruano, Luís& Cruz, Vítor Tedim& Veira, Carlos& Coutinho, Paula. 2012. Superficial Siderosis and Anticoagulation Therapy : Different Presentations, Different Outcomes. Case Reports in Neurological Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495327
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Barreto, Rui Duarte…[et al.]. Superficial Siderosis and Anticoagulation Therapy : Different Presentations, Different Outcomes. Case Reports in Neurological Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-495327
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Barreto, Rui Duarte& Ruano, Luís& Cruz, Vítor Tedim& Veira, Carlos& Coutinho, Paula. Superficial Siderosis and Anticoagulation Therapy : Different Presentations, Different Outcomes. Case Reports in Neurological Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-495327
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495327
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر