Effects of Phenolic Compounds of Fermented Thai Indigenous Plants on Oxidative Stress in Streptozotocin-Induced Diabetic Rats
المؤلفون المشاركون
Lerttrakarnnon, Peerasak
Chaiyasut, Chaiyavat
Kusirisin, Winthana
Suttajit, Maitree
Srichairatanakool, Somdet
Lailerd, Narissara
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-03-08
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
We investigated the effects of antioxidant activity of fermentation product (FP) of five Thai indigenous products on oxidative stress in Wistar rats with streptozotocin (STZ)-induced diabetes type II.
The rats were fed with placebo and with the FP (2 and 6 mL/kg body weight/day) for 6 weeks.
Rutin, pyrogallol and gallic acid were main compounds found in the FP.
Plasma glucose levels in diabetic rats receiving the higher dose of the FP increased less when compared to the diabetic control group as well as the group receiving the lower FP dose (13.1%, 29%, and 21.1%), respectively.
A significant dose-dependent decrease in plasma levels of thiobarbituric acid reactive substance (P<.05) was observed.
In addition, the doses of 2 and 6 mL FP/kg/day decreased the levels of erythrocyte ROS in diabetic rats during the experiment, but no difference was observed when compared to the untreated diabetic rat group.
Results imply that FP decreased the diabetes-associated oxidative stress to a large extent through the inhibition of lipid peroxidation.
The FP also improved the abnormal glucose metabolism slightly but the difference was not statistically significant.
Thus, FP may be a potential therapeutic agent by reducing injury caused by oxidative stress associated with diabetes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chaiyasut, Chaiyavat& Kusirisin, Winthana& Lailerd, Narissara& Lerttrakarnnon, Peerasak& Suttajit, Maitree& Srichairatanakool, Somdet. 2011. Effects of Phenolic Compounds of Fermented Thai Indigenous Plants on Oxidative Stress in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-495662
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chaiyasut, Chaiyavat…[et al.]. Effects of Phenolic Compounds of Fermented Thai Indigenous Plants on Oxidative Stress in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-495662
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chaiyasut, Chaiyavat& Kusirisin, Winthana& Lailerd, Narissara& Lerttrakarnnon, Peerasak& Suttajit, Maitree& Srichairatanakool, Somdet. Effects of Phenolic Compounds of Fermented Thai Indigenous Plants on Oxidative Stress in Streptozotocin-Induced Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-495662
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495662
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر