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Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.
المؤلفون المشاركون
Ong, Hui San
Firdaus-Raih, Mohd
Mohamed, Rahmah
المصدر
Comparative and Functional Genomics
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-06
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Members of the Burkholderia family occupy diverse ecological niches.
In pathogenic family members, glycan-associated proteins are often linked to functions that include virulence, protein conformation maintenance, surface recognition, cell adhesion, and immune system evasion.
Comparative analysis of available Burkholderia genomes has revealed a core set of 178 glycan-associated proteins shared by all Burkholderia of which 68 are homologous to known essential genes.
The genome sequence comparisons revealed insights into species-specific gene acquisitions through gene transfers, identified an S-layer protein, and proposed that significantly reactive surface proteins are associated to sugar moieties as a potential means to circumvent host defense mechanisms.
The comparative analysis using a curated database of search queries enabled us to gain insights into the extent of conservation and diversity, as well as the possible virulence-associated roles of glycan-associated proteins in members of the Burkholderia spp.
The curated list of glycan-associated proteins used can also be directed to screen other genomes for glycan-associated homologs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ong, Hui San& Mohamed, Rahmah& Firdaus-Raih, Mohd. 2012. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. Comparative and Functional Genomics،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-495988
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ong, Hui San…[et al.]. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. Comparative and Functional Genomics No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-495988
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ong, Hui San& Mohamed, Rahmah& Firdaus-Raih, Mohd. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. Comparative and Functional Genomics. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-495988
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495988
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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