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Development and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer
المؤلفون المشاركون
Suzuki, Hiroyoshi
Komaru, Atsushi
Miura, Junichiro
Utsumi, Takanobu
Kawamura, Koji
Fukasawa, Satoshi
Takano, Makoto
Imamoto, Takashi
Suyama, Takahito
Ueda, Takeshi
Ichikawa, Tomohiko
Kamiya, Naoto
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-11-07
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
The aim of this study is to develop a prognostic model capable of predicting the probability of significant upgrading among Japanese patients.
Methods.
The study cohort comprised 508 men treated with RP, with available prostate-specific antigen levels, biopsy, and RP Gleason sum values.
Clinical and pathological data from 258 patients were obtained from another Japanese institution for validation.
Results.
Significant Gleason sum upgrading was recorded in 92 patients (18.1%) at RP.
The accuracy of the nomogram predicting the probability of significant Gleason sum upgrading between biopsy and RP specimens was 88.9%.
Overall AUC was 0.872 when applied to the validation data set.
Nomogram predictions of significant upgrading were within 7.5% of an ideal nomogram.
Conclusions.
Nearly one-fifth of Japanese patients with prostate cancer will be significantly upgraded.
Our nomogram seems to provide considerably accurate predictions regardless of minor variations in pathological assessment when applied to Japanese patient populations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Imamoto, Takashi& Utsumi, Takanobu& Takano, Makoto& Komaru, Atsushi& Fukasawa, Satoshi& Suyama, Takahito…[et al.]. 2010. Development and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer. Prostate Cancer،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-496156
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Imamoto, Takashi…[et al.]. Development and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer. Prostate Cancer No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-496156
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Imamoto, Takashi& Utsumi, Takanobu& Takano, Makoto& Komaru, Atsushi& Fukasawa, Satoshi& Suyama, Takahito…[et al.]. Development and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer. Prostate Cancer. 2010. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-496156
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496156
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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