![](/images/graphics-bg.png)
The Extract of Herbal Medicines Activates AMP-Activated Protein Kinase in Diet-Induced Obese Rats
المؤلفون المشاركون
Chung, SaeYeon
Lee, Ji-Hye
Ko, Seong-Gyu
Kim, Soon Re
Shin, Yong Cheol
Seo, Hye-Sook
Shin, Hye-Yeon
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Our study investigated whether the extract of six herbal medicines (OB-1) has an inhibitory effect on obesity.
High-fat diet-(HFD-) induced rats and controls were treated with 40 mg/100 g body weight of OB-1 or saline once a day for 5 weeks.
After significant changes in body weight were induced, OB-1 and saline were administered to each subgroup of HFD and control groups for additional 5 weeks.
No statistically significant decrease of body weight in OB-1-treated rats was found compared to controls.
However, OB-1-treated rats were found to be more active in an open-field test and have a reduction in the size of adipocytes compared to controls.
We observed no changes in the mRNA expressions of leptin and adiponectin from adipocytes between OB-1- and saline-treated rats with HFD-induced obesity group.
However, OB-1 treatments were shown to be inversely correlated with accumulation of lipid droplets in liver tissue, suggesting that OB-1 could inhibit a lipid accumulation by blocking the pathway related to lipid metabolism.
Moreover, the phosphorylation of AMP-activated protein kinase (AMPK) was significantly increased in OB-1-treated rats with HFD compared to controls.
These results suggest that OB-1 has no direct antiobesity effect and, however, could be a regulator of cellular metabolism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shin, Hye-Yeon& Chung, SaeYeon& Kim, Soon Re& Lee, Ji-Hye& Seo, Hye-Sook& Shin, Yong Cheol…[et al.]. 2013. The Extract of Herbal Medicines Activates AMP-Activated Protein Kinase in Diet-Induced Obese Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496207
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shin, Hye-Yeon…[et al.]. The Extract of Herbal Medicines Activates AMP-Activated Protein Kinase in Diet-Induced Obese Rats. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-496207
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shin, Hye-Yeon& Chung, SaeYeon& Kim, Soon Re& Lee, Ji-Hye& Seo, Hye-Sook& Shin, Yong Cheol…[et al.]. The Extract of Herbal Medicines Activates AMP-Activated Protein Kinase in Diet-Induced Obese Rats. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496207
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496207
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)