Assessment of Wound Healing Activity of the Aqueous Extracts of Colutea cilicica Boiss. & Bal. Fruits and Leaves
المؤلفون المشاركون
Peşin Süntar, Ipek
Yılmazer, Demet
Akkol, Esra Küpeli
Koca, Ufuk
Alper, Murat
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The fruiting branches of Colutea cilicica Boiss.
& Bal., along with leaves and fruits, have been used to heal inflammatory wounds at traditional medicine in various parts of Turkey.
In order to evaluate the wound healing activity of the plant, aqueous extracts were prepared from the flowering parts and fruits of Colutea cilicica Boiss.
& Bal.
by using 40°C distilled water.
Incision wound healing models by using tensiometer on rats and excision wound healing models on mice were employed to assess the activity.
Significant wound healing activity was observed when ointment formulation of the aqueous extract at 1% concentration was applied on the mentioned models.
The fruit extract treated the groups of animals, showing a 78.1% contraction in wounds, which was close to the contraction value of the reference drug Madecassol (100%).
On the other hand, the same extract used on the incision wound model demonstrated a significant increase (42%) in wound tensile strength, compared to the flowering aerial parts.
Histopathological examination also supported the results shown in both the incision and excision wound models.
The wound healing effect was evaluated and compared with the reference ointment Madecassol.
Moreover, zinc and vitamin C levels in the fruit (9480 ± 0 mcg g−1; 389 mg g−1) and flowering aerial part (6609 ± 1 mcg g−1; 404 mg g−1) extracts, which might have contributed to the wound healing process, were determined.
The experimental data confirmed the traditional usage of C.
cilicica Boiss.
& Bal.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Peşin Süntar, Ipek& Koca, Ufuk& Akkol, Esra Küpeli& Yılmazer, Demet& Alper, Murat. 2011. Assessment of Wound Healing Activity of the Aqueous Extracts of Colutea cilicica Boiss. & Bal. Fruits and Leaves. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-496407
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Peşin Süntar, Ipek…[et al.]. Assessment of Wound Healing Activity of the Aqueous Extracts of Colutea cilicica Boiss. & Bal. Fruits and Leaves. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-496407
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Peşin Süntar, Ipek& Koca, Ufuk& Akkol, Esra Küpeli& Yılmazer, Demet& Alper, Murat. Assessment of Wound Healing Activity of the Aqueous Extracts of Colutea cilicica Boiss. & Bal. Fruits and Leaves. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-496407
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496407
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر