Pcr versus elisa in diagnosis of human toxoplasmosis in Jeddah, Saudi Arabia

الملخص EN

In this study, polymerase chain reaction (PCR) was compared with detection of specific antibodies to Toxoplasma by ELISA.

A total of 70 blood samples from patients with different clinical features were tested, 43 / 70 (61.4 %) were serologically Toxoplasma-IgG positive meanwhile only 16 / 43 (37.2 %) were approved to be positive by PCR.

A total of 22 samples (31.6 %) were positive by PCR, but only 16 of them were positive by ELISA.

So, Tox-IgG indicated catching Toxoplasma infection but not enough with immune modulation to determine acute case, while PCR besides, being valuable in diagnosis showed Toxoplasma parasitemia.