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Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans
المؤلفون المشاركون
Akinosun, Olubayo
Falase, Ayodele
Nwafor, Chibuike
Adebiyi, Adewole
المصدر
International Journal of Hypertension
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-07
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality.
Studies have suggested that the activity of the renin-angiotensin-aldosterone system play a major role in the target organ damage such as left ventricular hypertrophy occuring in hypertension.
We sought to determine the relationship between plasma aldosterone and left ventricular mass in untreated African hypertensives.
Methods.
We recruited 82 newly diagnosed and untreated hypertensives and 51 normal controls.
Measurements obtained included echocardiographic LV mass index, plasma aldosterone and renin.
Results.
The hypertensive subjects had lower renin levels (21.03[6.974] versus 26.66[7.592] ng.mL−1, P=0.0013), higher LV mass index (52.56[14.483] versus 42.02[8.315] g.m−2.7P<0.0001) when compared with the controls.
There were no univariate associations between LV mass index and plasma aldosterone (r=0.0179, P=0.57) and between LV mass index and plasma renin (r=0.0887, P=0.61).
In a multivariate model involving LV mass index and age, sex, body mass index (BMI), plasma aldosterone, plasma renin and systolic blood pressure (SBP), only age (P=0.008), BMI (P=0.046), and SBP (P=0.001) were independently associated with the LV mass index.
Conclusions.
In this group of hypertensive Africans, there is no independent association of plasma aldosterone with LV mass.
The height of the blood pressure, the body mass index and the age of the subjects determined the LV mass.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adebiyi, Adewole& Akinosun, Olubayo& Nwafor, Chibuike& Falase, Ayodele. 2013. Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-496802
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adebiyi, Adewole…[et al.]. Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans. International Journal of Hypertension No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-496802
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adebiyi, Adewole& Akinosun, Olubayo& Nwafor, Chibuike& Falase, Ayodele. Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-496802
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496802
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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