Diffusion-Weighted Magnetic Resonance Diagnosis of Local Recurrences of Prostate Cancer after Radical Prostatectomy : Preliminary Evaluation on Twenty-Seven Cases
المؤلفون المشاركون
Volterrani, Luca
Cacchiarelli, Eleonora
Ricci, Veronica
Carbone, Salvatore Francesco
La Penna, Augusto
Tini, Paolo
Pirtoli, Luigi
Carfagno, Tommaso
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-16
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives.
To assess the diagnostic performance of diffusion-weighted MR imaging (DWI) in patients affected by prostatic fossa (PF) relapse after radical prostatectomy (RP) for prostatic carcinoma (PC).
Methods.
Twenty-seven patients showing a nodular lesion in the PF at T2-weighted MR imaging after RP, with diagnosis of PC relapse established by biopsy or PSA determinations, were investigated by DWI.
Two readers evaluated the DWI results in consensus and the apparent diffusion coefficient (ADC) of the nodules, separately; a mean value was obtained (ADCm).
Results.
Relapses did not significantly differ in size in respect of postsurgical benign nodules.
The DWI qualitative evaluation showed sensitivity, specificity, accuracy, ppv, and npv values, respectively, of 83.3%, 88.9%, 85.2%, 93.7%, and 72.7% (100%, 87.5%, 95.6%, 93.7%, and 100%, for nodules >6 mm).
The intraclass correlation coefficient (ICC) for ADC evaluation between the two readers was 0.852 (95% CI 0.661–0.935; P=0.0001).
The ADCm values for relapses and benign nodules were, respectively, 0.98±0.21×10−3 mm2/sec and 1.24±0.32×10−3 mm2/sec (P=0.006).
Sensitivity, specificity, accuracy, ppv and npv of ADCm were, respectively, 77.8%, 88.9%, 81.8%, 93.3%, and 66.7% (93.3%, 87.5%, 85.4%, 93.3%, and 87.5% for nodules >6 mm).
Conclusions.
Diffusion-weighted MR imaging is a promising tool in the management of a hyperintense nodule detected by T2-weighted sequences.
This might have a relevant importance in contouring radiotherapy treatment volumes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Carbone, Salvatore Francesco& Pirtoli, Luigi& Ricci, Veronica& Carfagno, Tommaso& Tini, Paolo& La Penna, Augusto…[et al.]. 2014. Diffusion-Weighted Magnetic Resonance Diagnosis of Local Recurrences of Prostate Cancer after Radical Prostatectomy : Preliminary Evaluation on Twenty-Seven Cases. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-497456
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Carbone, Salvatore Francesco…[et al.]. Diffusion-Weighted Magnetic Resonance Diagnosis of Local Recurrences of Prostate Cancer after Radical Prostatectomy : Preliminary Evaluation on Twenty-Seven Cases. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-497456
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Carbone, Salvatore Francesco& Pirtoli, Luigi& Ricci, Veronica& Carfagno, Tommaso& Tini, Paolo& La Penna, Augusto…[et al.]. Diffusion-Weighted Magnetic Resonance Diagnosis of Local Recurrences of Prostate Cancer after Radical Prostatectomy : Preliminary Evaluation on Twenty-Seven Cases. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-497456
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497456
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر