Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy : Observations with Oral Acitretin
المؤلفون المشاركون
Errichetti, Enzo
Patrone, Pasquale
Stinco, Giuseppe
Valent, Francesca
Buligan, Cinzia
المصدر
Dermatology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-23
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Psoriasis is considered to be an inflammatory autoimmune disease, where angiogenesis plays an undefined pathogenetic role.
The well-known changes of the superficial microvasculature in the psoriatic plaque can be easily assessed in vivo by videocapillaroscopy.
In the last years, several studies reported the clinical and capillaroscopic response of the psoriatic plaque during different topical and systemic treatments.
In the present work we evaluated the effects of acitretin (0.8 mg/kg/day) on videocapillaroscopic alterations and the clinical response in 11 patients affected by plaque psoriasis at the baseline (T0) and after 4 (T1), 8 (T2), and 12 (T3) weeks.
A clinical improvement during the treatment with a complete clinical healing of the plaque in 7 of the 11 patients was observed.
The typical “basket-weave” capillaries of the psoriatic lesions showed a reduction of 65.4% in diameter at the end of the study; only 3 patients returned to a normal capillaroscopic pattern.
As observed during previous our studies, we found a discrepancy between clinical and capillaroscopic results, with a far greater improvement in the first than in the second.
This finding could be in agreement with a secondary role of blood vessels in the pathogenesis and persistence of psoriatic lesions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Stinco, Giuseppe& Buligan, Cinzia& Errichetti, Enzo& Valent, Francesca& Patrone, Pasquale. 2013. Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy : Observations with Oral Acitretin. Dermatology Research and Practice،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-497564
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Stinco, Giuseppe…[et al.]. Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy : Observations with Oral Acitretin. Dermatology Research and Practice No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-497564
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Stinco, Giuseppe& Buligan, Cinzia& Errichetti, Enzo& Valent, Francesca& Patrone, Pasquale. Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy : Observations with Oral Acitretin. Dermatology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-497564
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497564
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر