No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population
المؤلفون المشاركون
Erlwein, Otto
McClure, Myra O.
Naresh, Kikkeri N.
Gopalakrishnan, Ganesh
Tuke, Philip William
Robinson, Mark James
Patel, Anup
Kaye, Steve
Tettmar, Kate I.
Walker, Marjorie M.
Tedder, Richard S.
Kimura, Takahiro
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Xenotropic murine leukaemia virus-related virus (XMRV) is a recently described retrovirus which has been claimed to infect humans and cause associated pathology.
Initially identified in the US in patients with prostate cancer and subsequently in patients with chronic fatigue syndrome, doubt now exists that XMRV is a human pathogen.
We studied the prevalence of genetic sequences of XMRV and related MuLV sequences in human prostate cancer, from B cell lymphoma patients and from UK blood donors.
Nucleic acid was extracted from fresh prostate tissue biopsies, formalin-fixed paraffin-embedded (FFPE) prostate tissue and FFPE B-cell lymphoma.
The presence of XMRV-specific LTR or MuLV generic gag-like sequences was investigated by nested PCR.
To control for mouse DNA contamination, a PCR that detected intracisternal A-type particle (IAP) sequences was included.
In addition, DNA and RNA were extracted from whole blood taken from UK blood donors and screened for XMRV sequences by real-time PCR.
XMRV or MuLV-like sequences were not amplified from tissue samples.
Occasionally MuLV gag and XMRV-LTR sequences were amplified from Indian prostate cancer samples, but were always detected in conjunction with contaminating murine genomic DNA.
We found no evidence of XMRV or MuLV infection in the UK blood donors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Robinson, Mark James& Tuke, Philip William& Erlwein, Otto& Tettmar, Kate I.& Kaye, Steve& Naresh, Kikkeri N.…[et al.]. 2011. No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population. Advances in Virology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-497604
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Robinson, Mark James…[et al.]. No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population. Advances in Virology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-497604
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Robinson, Mark James& Tuke, Philip William& Erlwein, Otto& Tettmar, Kate I.& Kaye, Steve& Naresh, Kikkeri N.…[et al.]. No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population. Advances in Virology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-497604
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497604
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر