Effect of Highly Active Antiretroviral Therapy (HAART) and Menopause on Risk of Progression of Cervical Dysplasia in Human Immune-Deficiency Virus- (HIV-) Infected Women
المؤلفون المشاركون
Kim, Suk Chul
Messing, Susan
Luque, Amneris E.
Shah, Krupa
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
More HIV-infected women are reaching older age and menopause, but there is limited information on cervical squamous intraepithelial lesions (SILs) on these women.
Methods.
To assess the effect of HAART and menopause on SILs in HIV-infected women, we reviewed the results of Papanicolaou (Pap) tests obtained between 1991 and 2011 on 245 women.
Progression to SILs was determined by comparing Pap test results.
The association of HAART and transition to menopause on SILs was assessed using survival analysis.
Results.
Women receiving HAART had a 52% reduced risk in the progression to SILs compared to women receiving any other antiretroviral regimen or no regimen (CI: 0.33–0.70, P=0.0001).
A greater increase of CD4+ cell counts was associated with a greater reduction on the risk of progression to SILs.
Menopausal women had a 70% higher risk of progression to SILs than premenopausal women (CI: 1.11–2.62, P<0.0001), adjusting for HIV medications, CD4+ count, duration of HIV infection, moderation effect of menopause by age, prior IV drug use, and smoking.
Conclusion.
HAART had a positive long-term effect on the progression to SILs.
However, being younger and menopausal increases the risk of progression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Suk Chul& Messing, Susan& Shah, Krupa& Luque, Amneris E.. 2013. Effect of Highly Active Antiretroviral Therapy (HAART) and Menopause on Risk of Progression of Cervical Dysplasia in Human Immune-Deficiency Virus- (HIV-) Infected Women. Infectious Diseases in Obstetrics and Gynecology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497850
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Suk Chul…[et al.]. Effect of Highly Active Antiretroviral Therapy (HAART) and Menopause on Risk of Progression of Cervical Dysplasia in Human Immune-Deficiency Virus- (HIV-) Infected Women. Infectious Diseases in Obstetrics and Gynecology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-497850
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Suk Chul& Messing, Susan& Shah, Krupa& Luque, Amneris E.. Effect of Highly Active Antiretroviral Therapy (HAART) and Menopause on Risk of Progression of Cervical Dysplasia in Human Immune-Deficiency Virus- (HIV-) Infected Women. Infectious Diseases in Obstetrics and Gynecology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-497850
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497850
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر