Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis
المؤلفون المشاركون
Rivera, Adriana
Younger, John G.
Sharma, Prannda
Newton, Duane W.
Satorius, Ashley E.
Raff, Marika R.
المصدر
Interdisciplinary Perspectives on Infectious Diseases
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-02
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Staphylococcus epidermidis is an important cause of nosocomial infection and bacteremia.
It is also a common contaminant of blood cultures and, as a result, there is frequently uncertainty as to its diagnostic significance when recovered in the clinical laboratory.
One molecular strategy that might be of value in clarifying the interpretation of S.
epidermidis identified in blood culture is multilocus sequence typing.
Here, we examined 100 isolates of this species (50 blood isolates representing true bacteremia, 25 likely contaminant isolates, and 25 skin isolates) and the ability of sequence typing to differentiate them.
Three machine learning algorithms (classification regression tree, support vector machine, and nearest neighbor) were employed.
Genetic variability was substantial between isolates, with 44 sequence types found in 100 isolates.
Sequence types 2 and 5 were most commonly identified.
However, among the classification algorithms we employed, none were effective, with CART and SVM both yielding only 73% diagnostic accuracy and nearest neighbor analysis yielding only 53% accuracy.
Our data mirror previous studies examining the presence or absence of pathogenic genes in that the overlap between truly significant organisms and contaminants appears to prevent the use of MLST in the clarification of blood cultures recovering S.
epidermidis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sharma, Prannda& Satorius, Ashley E.& Raff, Marika R.& Rivera, Adriana& Newton, Duane W.& Younger, John G.. 2014. Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-498099
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sharma, Prannda…[et al.]. Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis. Interdisciplinary Perspectives on Infectious Diseases No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-498099
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sharma, Prannda& Satorius, Ashley E.& Raff, Marika R.& Rivera, Adriana& Newton, Duane W.& Younger, John G.. Multilocus Sequence Typing for Interpreting Blood Isolates of Staphylococcus epidermidis. Interdisciplinary Perspectives on Infectious Diseases. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-498099
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498099
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر