Copy-Number Variations Observed in a Japanese Population by BAC Array CGH : Summary of Relatively Rare CNVs
المؤلفون المشاركون
Takahashi, Norio
Sasaki, Keiko
Shimoichi, Yuko
Katayama, Hiroaki
Satoh, Yasunari
Sugita, Keiko
المصدر
Journal of Biomedicine and Biotechnology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-24
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Copy-number variations (CNVs) may contribute to genetic variation in humans.
Reports regarding existence and characteristics of CNVs in a large apparently healthy Japanese cohort are quite limited.
We report the data from a screening of 213 unrelated Japanese individuals using comparative genomic hybridization based on a bacterial artificial chromosome microarray (BAC aCGH).
In a previous paper, we summarized the data by focusing on highly polymorphic CNVs (in ≥5.0 % of the individuals).
However, rare variations have recently received attention from scientists who espouse a hypothesis called “common disease and rare variants.” Here, we report CNVs identified in fewer than 10 individuals in our study population.
We found a total of 126 CNVs at 52 different BAC regions in the genome.
The CNVs observed at 27 of the 52 BAC-regions were found in only one unrelated individual.
The majority of CNVs found in this study were not identified in the Japanese who were examined in the other studies.
Family studies were conducted, and the results demonstrated that the CNVs were inherited from one parent in the families.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Satoh, Yasunari& Sasaki, Keiko& Shimoichi, Yuko& Sugita, Keiko& Katayama, Hiroaki& Takahashi, Norio. 2012. Copy-Number Variations Observed in a Japanese Population by BAC Array CGH : Summary of Relatively Rare CNVs. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-498136
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Satoh, Yasunari…[et al.]. Copy-Number Variations Observed in a Japanese Population by BAC Array CGH : Summary of Relatively Rare CNVs. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-498136
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Satoh, Yasunari& Sasaki, Keiko& Shimoichi, Yuko& Sugita, Keiko& Katayama, Hiroaki& Takahashi, Norio. Copy-Number Variations Observed in a Japanese Population by BAC Array CGH : Summary of Relatively Rare CNVs. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-498136
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498136
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر