A Chinese Herbal Preparation Containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum Reduces Circulating Adhesion Molecules
المؤلفون المشاركون
Luo, Ruizhi
Wang, Wen Cheng
Guo, Zhi-Xin
Komesaroff, Paul A.
Bensoussan, Alan
Dai, Aozhi
Abbas, Estelle
Ling, Shanhong
Zhang, Jiansheng
O'Brien, Kylie A.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Circulating adhesion molecules (CAMs), surface proteins expressed in the vascular endothelium, have emerged as risk factors for cardiovascular disease (CVD).
CAMs are involved in intercellular communication that are believed to play a role in atherosclerosis.
A Chinese medicine, the “Dantonic Pill” (DP) (also known as the “Cardiotonic Pill”), containing three Chinese herbal material medica, Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum, has been used in China for the prevention and management of CVD.
Previous laboratory and animal studies have suggested that this preparation reduces both atherogenesis and adhesion molecule expression.
A parallel double blind randomized placebo-controlled study was conducted to assess the effects of the DP on three species of CAM (intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 and endothelial cell selectin (E-selectin)) in participants with mild-moderate hypercholesterolemia.
Secondary endpoints included biochemical and hematological variables and clinical effects.
Forty participants were randomized to either treatment or control for 12 weeks.
Treatment with DP was associated with a statistically significant decrease in ICAM-1 (9% decrease, P = .03) and E-Selectin (15% decrease, P = .004).
There was no significant change in renal function tests, liver function tests, glucose, lipids or C-reactive protein levels and clinical adverse effects did not differ between the active and the control groups.
There were no relevant changes in participants receiving placebo.
These results suggest that this herbal medicine may contribute to the development of a novel approach to cardiovascular risk reduction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
O'Brien, Kylie A.& Ling, Shanhong& Abbas, Estelle& Dai, Aozhi& Zhang, Jiansheng& Wang, Wen Cheng…[et al.]. 2011. A Chinese Herbal Preparation Containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum Reduces Circulating Adhesion Molecules. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-498334
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
O'Brien, Kylie A.…[et al.]. A Chinese Herbal Preparation Containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum Reduces Circulating Adhesion Molecules. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-498334
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
O'Brien, Kylie A.& Ling, Shanhong& Abbas, Estelle& Dai, Aozhi& Zhang, Jiansheng& Wang, Wen Cheng…[et al.]. A Chinese Herbal Preparation Containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum Reduces Circulating Adhesion Molecules. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-498334
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498334
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر