Biliary Adenofibroma with Carcinoma In Situ : A Rare Case Report

الملخص EN

This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman.

This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma.

This is the seventh case described in the literature.

Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation.

It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign.