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Evaluation of Oral Robenacoxib for the Treatment of Postoperative Pain and Inflammation in Cats : Results of a Randomized Clinical Trial
المؤلفون المشاركون
King, Jonathan N.
Roberts, Elizabeth S.
Roycroft, Linda M.
King, Stephen
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The efficacy and safety of robenacoxib were assessed for the control of postoperative pain and inflammation in cats.
The study was a multicenter, prospective, randomized, blinded, and parallel group clinical trial.
A total of 249 client-owned cats scheduled for forelimb onychectomy plus either ovariohysterectomy or castration surgeries were included.
All cats received butorphanol prior to anesthesia and forelimb four-point regional nerve blocks with bupivacaine after induction of general anesthesia.
Cats were randomized to receive daily oral tablet robenacoxib, at a mean (range) dosage of 1.84 (1.03–2.40) mg/kg (n=167), or placebo (n=82), once prior to surgery and for two days postoperatively.
Significantly (P<0.05) fewer robenacoxib cats received additional analgesia rescue therapy (16.5%) than placebo cats (46.3%).
Pain elicited on palpation of the soft tissue incision site, behavior following social interaction, and posture assessed during the first 8 hours after extubation were significantly (P<0.05) improved in cats receiving robenacoxib.
Frequency of reported adverse clinical signs, hematology, serum chemistry and urinalysis variables, and body weight changes weresimilar between groups.
In conclusion, robenacoxib was effective and well tolerated in the control of postoperative pain and inflammation in cats undergoing onychectomy with ovariohysterectomy or castration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
King, Stephen& Roberts, Elizabeth S.& Roycroft, Linda M.& King, Jonathan N.. 2012. Evaluation of Oral Robenacoxib for the Treatment of Postoperative Pain and Inflammation in Cats : Results of a Randomized Clinical Trial. ISRN Veterinary Science،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-498651
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
King, Stephen…[et al.]. Evaluation of Oral Robenacoxib for the Treatment of Postoperative Pain and Inflammation in Cats : Results of a Randomized Clinical Trial. ISRN Veterinary Science No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-498651
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
King, Stephen& Roberts, Elizabeth S.& Roycroft, Linda M.& King, Jonathan N.. Evaluation of Oral Robenacoxib for the Treatment of Postoperative Pain and Inflammation in Cats : Results of a Randomized Clinical Trial. ISRN Veterinary Science. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-498651
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498651
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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