Short-Term Rationing of Combination Antiretroviral Therapy : Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya
المؤلفون المشاركون
Sidle, John E.
Kimaiyo, Sylvester
Simiyu, Gilbert
Katschke, Adrian
Bell, April J.
Braitstein, Paula
Musick, Beverly S.
Liu, Hai
Wools-Kaloustian, Kara K.
Siika, Abraham M.
Shen, Changyu
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
There was a 6-month shortage of antiretrovirals (cART) in Kenya.
Methods.
We assessed morbidity, mortality, and loss to follow-up (LTFU) in this retrospective analysis of adults who were enrolled during the six-month period with restricted cART (cap) or the six months prior (pre-cap) and eligible for cART at enrollment by the pre-cap standard.
Cox models were used to adjust for potential confounders.
Results.
9009 adults were eligible for analysis: 4,714 pre-cap and 4,295 during the cap.
Median number of days from enrollment to cART initiation was 42 pre-cap and 56 for the cap (P<0.001).
After adjustment, individuals in the cap were at higher risk of mortality (HR=1.21; 95% CI : 1.06–1.39) and LTFU (HR=1.12; 95% CI : 1.04–1.22).
There was no difference between the groups in their risk of developing a new AIDS-defining illness (HR=0.92 95% CI 0.82–1.03).
Conclusions.
Rationing of cART, even for a relatively short period of six months, led to clinically adverse outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bell, April J.& Wools-Kaloustian, Kara K.& Kimaiyo, Sylvester& Liu, Hai& Katschke, Adrian& Shen, Changyu…[et al.]. 2012. Short-Term Rationing of Combination Antiretroviral Therapy : Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-500212
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bell, April J.…[et al.]. Short-Term Rationing of Combination Antiretroviral Therapy : Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya. AIDS Research and Treatment No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-500212
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bell, April J.& Wools-Kaloustian, Kara K.& Kimaiyo, Sylvester& Liu, Hai& Katschke, Adrian& Shen, Changyu…[et al.]. Short-Term Rationing of Combination Antiretroviral Therapy : Impact on Morbidity, Mortality, and Loss to Follow-Up in a Large HIV Treatment Program in Western Kenya. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-500212
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500212
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر