Hyperacute Corticosteroid Treatment of Optic Neuritis at the Onset of Pain May Prevent Visual Loss : A Case Series
المؤلفون المشاركون
Plant, Gordon T.
Sibtain, N. A.
Thomas, D.
المصدر
Multiple Sclerosis International
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
To show that high-dose corticosteroids may prevent visual loss in patients with optic neuritis (ON) treated at the prodromal, hyperacute, phase of retrobulbar pain.
Method.
Prospective case series: patients were recruited with a history of ON associated with pain.
The patients were advised to report immediately to the investigators should the pain recur in either eye.
Where possible, orbital magnetic resonance imaging (MRI) was performed to confirm a recurrence of ON and treatment with high-dose corticosteroids was commenced.
Visual function and the patient's subjective account were monitored.
Results.
Eight patients (including cases of MS, CRION and NMO) presented in the hyperacute phase.
MRI confirmed optic nerve inflammation in 5/5.
Treatment was commenced immediately, and, in all cases, no visual loss ensued.
Conclusion.
MRI can be used to confirm acute optic neuritis prior to visual loss in the hyperacute phase.
We suggest that treatment with high-dose corticosteroids may abort the attack and prevent loss of vision in patients with ON who are treated at the onset of pain.
This has potential implications for the management of acute ON and also for our understanding of the pathogenesis and potential therapeutic targets in the neuroinflammatory conditions associated with ON.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Plant, Gordon T.& Sibtain, N. A.& Thomas, D.. 2011. Hyperacute Corticosteroid Treatment of Optic Neuritis at the Onset of Pain May Prevent Visual Loss : A Case Series. Multiple Sclerosis International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-500276
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Plant, Gordon T.…[et al.]. Hyperacute Corticosteroid Treatment of Optic Neuritis at the Onset of Pain May Prevent Visual Loss : A Case Series. Multiple Sclerosis International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-500276
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Plant, Gordon T.& Sibtain, N. A.& Thomas, D.. Hyperacute Corticosteroid Treatment of Optic Neuritis at the Onset of Pain May Prevent Visual Loss : A Case Series. Multiple Sclerosis International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-500276
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500276
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر