Andrographolide : A New Plant-Derived Antineoplastic Entity on Horizon
المؤلفون المشاركون
Shrivastava, Neeta
Varma, Astha
Padh, Harish
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-10
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Plant-derived natural products occupy an important position in the area of cancer chemotherapy.
Molecules such as vincristine, vinblastine, paclitaxel, camptothecin derivatives, epipodophyllotoxin, and so forth, are invaluable contributions of nature to modern medicine.
However, the quest to find out novel therapeutic compounds for cancer treatment and management is a never-ending venture; and diverse plant species are persistently being studied for identification of prospective anticancer agents.
In this regard, Andrographis paniculata Nees, a well-known plant of Indian and Chinese traditional system of medicines, has drawn attention of researchers in recent times.
Andrographolide, the principal bioactive chemical constituent of the plant has shown credible anticancer potential in various investigations around the globe.
In vitro studies demonstrate the capability of the compound of inducing cell-cycle arrest and apoptosis in a variety of cancer cells at different concentrations.
Andrographolide also shows potent immunomodulatory and anti-angiogenic activities in tumorous tissues.
Synthetic analogues of the compound have also been created and analyzed, which have also shown similar activities.
Although it is too early to predict its future in cancer chemotherapy, the prologue strongly recommends further research on this molecule to assess its potential as a prospective anticancer agent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Varma, Astha& Padh, Harish& Shrivastava, Neeta. 2011. Andrographolide : A New Plant-Derived Antineoplastic Entity on Horizon. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-500308
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Varma, Astha…[et al.]. Andrographolide : A New Plant-Derived Antineoplastic Entity on Horizon. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-500308
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Varma, Astha& Padh, Harish& Shrivastava, Neeta. Andrographolide : A New Plant-Derived Antineoplastic Entity on Horizon. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-500308
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500308
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر