Serum Lipid Profiles and Cancer Risk in the Context of Obesity : Four Meta-Analyses
المؤلفون المشاركون
Melvin, Jennifer C.
Rohrmann, Sabine
Holmberg, Lars
Loda, Massimo
Van Hemelrijck, Mieke
المصدر
Journal of Cancer Epidemiology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-20
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
The objective here was to summarize the evidence for, and quantify the link between, serum markers of lipid metabolism and risk of obesity-related cancers.
PubMed and Embase were searched using predefined inclusion criteria to conduct meta-analyses on the association between serum levels of TG, TC, HDL, ApoA-I, and risk of 11 obesity-related cancers.
Pooled relative risks (RRs) and 95% confidence intervals were estimated using random-effects analyses.
28 studies were included.
Associations between abnormal lipid components and risk of obesity-related cancers when using clinical cutpoints (TC≥6.50; TG≥1.71; HDL≤1.03; ApoA-I≤1.05 mmol/L) were apparent in all models.
RRs were 1.18 (95% CI: 1.08–1.29) for TC, 1.20 (1.07–1.35) for TG, 1.15 (1.01–1.32) for HDL, and 1.42 (1.17–1.74) for ApoA-I.
High levels of TC and TG, as well as low levels of HDL and ApoA-I, were consistently associated with increased risk of obesity-related cancers.
The modest RRs suggest serum lipids to be associated with the risk of cancer, but indicate it is likely that other markers of the metabolism and/or lifestyle factors may also be involved.
Future intervention studies involving lifestyle modification would provide insight into the potential biological role of lipid metabolism in tumorigenesis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Melvin, Jennifer C.& Holmberg, Lars& Rohrmann, Sabine& Loda, Massimo& Van Hemelrijck, Mieke. 2013. Serum Lipid Profiles and Cancer Risk in the Context of Obesity : Four Meta-Analyses. Journal of Cancer Epidemiology،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-500995
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Melvin, Jennifer C.…[et al.]. Serum Lipid Profiles and Cancer Risk in the Context of Obesity : Four Meta-Analyses. Journal of Cancer Epidemiology No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-500995
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Melvin, Jennifer C.& Holmberg, Lars& Rohrmann, Sabine& Loda, Massimo& Van Hemelrijck, Mieke. Serum Lipid Profiles and Cancer Risk in the Context of Obesity : Four Meta-Analyses. Journal of Cancer Epidemiology. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-500995
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500995
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر