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Simulations of Complex and Microscopic Models of Cardiac Electrophysiology Powered by Multi-GPU Platforms
المؤلفون المشاركون
Gouvêa de Barros, Bruno
Meira, Wagner
Weber dos Santos, Rodrigo
Lobosco, Marcelo
Sachetto Oliveira, Rafael
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-25
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Key aspects of cardiac electrophysiology, such as slow conduction, conduction block, and saltatory effects have been the research topic of many studies since they are strongly related to cardiac arrhythmia, reentry, fibrillation, or defibrillation.
However, to reproduce these phenomena the numerical models need to use subcellular discretization for the solution of the PDEs and nonuniform, heterogeneous tissue electric conductivity.
Due to the high computational costs of simulations that reproduce the fine microstructure of cardiac tissue, previous studies have considered tissue experiments of small or moderate sizes and used simple cardiac cell models.
In this paper, we develop a cardiac electrophysiology model that captures the microstructure of cardiac tissue by using a very fine spatial discretization (8 μm) and uses a very modern and complex cell model based on Markov chains for the characterization of ion channel’s structure and dynamics.
To cope with the computational challenges, the model was parallelized using a hybrid approach: cluster computing and GPGPUs (general-purpose computing on graphics processing units).
Our parallel implementation of this model using a multi-GPU platform was able to reduce the execution times of the simulations from more than 6 days (on a single processor) to 21 minutes (on a small 8-node cluster equipped with 16 GPUs, i.e., 2 GPUs per node).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gouvêa de Barros, Bruno& Sachetto Oliveira, Rafael& Meira, Wagner& Lobosco, Marcelo& Weber dos Santos, Rodrigo. 2012. Simulations of Complex and Microscopic Models of Cardiac Electrophysiology Powered by Multi-GPU Platforms. Computational and Mathematical Methods in Medicine،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-501062
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gouvêa de Barros, Bruno…[et al.]. Simulations of Complex and Microscopic Models of Cardiac Electrophysiology Powered by Multi-GPU Platforms. Computational and Mathematical Methods in Medicine No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-501062
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gouvêa de Barros, Bruno& Sachetto Oliveira, Rafael& Meira, Wagner& Lobosco, Marcelo& Weber dos Santos, Rodrigo. Simulations of Complex and Microscopic Models of Cardiac Electrophysiology Powered by Multi-GPU Platforms. Computational and Mathematical Methods in Medicine. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-501062
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501062
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