An n-of-1 Trial Service in Clinical Practice : Testing the Effectiveness of Liuwei Dihuang Decoction for Kidney-Yin Deficiency Syndrome
المؤلفون المشاركون
Baohe, Wang
Shujing, Yu
Shuxuan, Zou
Qian, Liu
Yanfen, Li
Yu, Liu
Lanjun, Sun
Yuhong, Huang
Yingqiang, Zhao
Shufang, Qin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To describe the clinical use of n-of-1 RCTs for kidney-Yin deficiency syndrome that is a traditional Chinese medicine syndrome in publicly clinical practice in China.
Methods.
Our study included patients with kidney-Yin deficiency syndrome, using a within-patient, randomized, double-blind, crossover comparison of Liuwei Dihuang decoction versus placebo.
Outcome Measures.
Primary outcome measures included number of individual completion rates, response rate, and post-n-of-1 RCTs decisions.
Secondary measures were the whole group score of individual Likert scale, SF-36 questionnaire.
Results.
Fifty patients were recruited and 3 were not completed.
Forty-seven patients completed 3 pairs of periods, 3 (6.38%) were responders, 28 (59.57%) were nonresponders, and 16 (34.05%) were possible responders.
Doctors and patients used the trial results to making decision.
Three responders stayed on the medication management, 28 nonresponders ceased the LDD, 7 patients of the 16 possible responders could not give clear decision, and the others kept the same medication station.
Among the whole group, neither the individual Likert score nor the SF-36 showed any statistical differences between LDD and placebo.
Discussion.
More attention should be paid to choose experienced TCM doctor as investigator and keep the simulant same with test medication in n-of-1 RCTs of TCM and sufficiently biological half-life period of Chinese medicine compound.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yuhong, Huang& Qian, Liu& Yu, Liu& Yingqiang, Zhao& Yanfen, Li& Shujing, Yu…[et al.]. 2013. An n-of-1 Trial Service in Clinical Practice : Testing the Effectiveness of Liuwei Dihuang Decoction for Kidney-Yin Deficiency Syndrome. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-501374
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yuhong, Huang…[et al.]. An n-of-1 Trial Service in Clinical Practice : Testing the Effectiveness of Liuwei Dihuang Decoction for Kidney-Yin Deficiency Syndrome. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-501374
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yuhong, Huang& Qian, Liu& Yu, Liu& Yingqiang, Zhao& Yanfen, Li& Shujing, Yu…[et al.]. An n-of-1 Trial Service in Clinical Practice : Testing the Effectiveness of Liuwei Dihuang Decoction for Kidney-Yin Deficiency Syndrome. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-501374
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501374
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر