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Clinical Effectiveness of Peramivir in Comparison with Other Neuraminidase Inhibitors in Pediatric Influenza Patients
المؤلفون المشاركون
Hikita, Naoko
Hikita, Toshiyuki
Hikita, Hiroyuki
Hikita, Fusako
Hikita, Shizue
المصدر
International Journal of Pediatrics
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-22
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
The currently used antivirals in the treatment of influenza in Japan include amantadine, oseltamivir, zanamivir, laninamivir, and peramivir.
We compared the efficacy of intravenous peramivir with that of other neuraminidase inhibitors for treating pediatric influenza.
The present study included 223 influenza patients (≤18 years) who presented at the Hikita Pediatric Clinic between February and April 2011.
We compared fever duration after starting treatment with antiviral drugs.
Because inhalation drugs are difficult to use in <5-year-old patients and because of the potential adverse effects of oseltamivir in teenagers, we created two different age groups (<10-year-old group and 5–18-year-old group) to evaluate treatment results.
In influenza A patients between 5 and 18 years old, the median fever duration after treatment with zanamivir was 2 days, compared with 1 day for peramivir (P=0.0242).
In influenza B patients between 5 and 18 years old, the median fever duration after treatment with laninamivir was 3 days, compared with 1 day for peramivir (P=0.0097).
We found no significant difference for any of the other combinations of drug/disease type/age groups.
No adverse effects were observed with the antiviral drugs used.
The results suggest that peramivir is very useful in pediatric influenza patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hikita, Toshiyuki& Hikita, Hiroyuki& Hikita, Fusako& Hikita, Naoko& Hikita, Shizue. 2012. Clinical Effectiveness of Peramivir in Comparison with Other Neuraminidase Inhibitors in Pediatric Influenza Patients. International Journal of Pediatrics،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501817
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hikita, Toshiyuki…[et al.]. Clinical Effectiveness of Peramivir in Comparison with Other Neuraminidase Inhibitors in Pediatric Influenza Patients. International Journal of Pediatrics No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-501817
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hikita, Toshiyuki& Hikita, Hiroyuki& Hikita, Fusako& Hikita, Naoko& Hikita, Shizue. Clinical Effectiveness of Peramivir in Comparison with Other Neuraminidase Inhibitors in Pediatric Influenza Patients. International Journal of Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501817
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501817
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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