Clinical Behavior in Metastatic Brain Disease Is Not Influenced by the Immunological Defense Mediated by CD57+ NK-Cells
المؤلفون المشاركون
Zurita, Mercedes
Vaquero, Jesús
Coca, Santiago
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-14
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Objectives.
The purpose of the present study is to verify if the degree of immunological response against metastatic tumors, measured by the number of CD57+ NK-cells in the tissue of a brain metastasis, influences the later development of new brain metastases or tumor recurrence.
Patients and Methods.
CD57+ NK-cells were immunohistochemically identified in the resected tumor, in a series of twenty patients operated on by a single brain metastasis secondary to lung adenocarcinoma.
In each case, the degree of CD57+ NK-cells infiltration within the tumor tissue and the period free of new intracranial disease after brain surgery were recorded.
Results.
All the studied tumors showed variable number of CD57+ NK-cells (mean ± standard deviation: 8.4±4.8 per microscopical field, at 200x).
The period free of intracranial disease ranged between 10 and 52 weeks (mean ± standard deviation: 22.7±11.9).
Statistical analysis showed that there was no correlation between the degree of NK-cells infiltration within the resected tumor and the period free of intracranial disease after surgery (P>0.05).
Conclusion.
This finding supports that clinical behavior in metastatic brain disease is not influenced by the immunological response mediated by CD57+ NK-cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vaquero, Jesús& Zurita, Mercedes& Coca, Santiago. 2011. Clinical Behavior in Metastatic Brain Disease Is Not Influenced by the Immunological Defense Mediated by CD57+ NK-Cells. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501875
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vaquero, Jesús…[et al.]. Clinical Behavior in Metastatic Brain Disease Is Not Influenced by the Immunological Defense Mediated by CD57+ NK-Cells. International Journal of Surgical Oncology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-501875
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vaquero, Jesús& Zurita, Mercedes& Coca, Santiago. Clinical Behavior in Metastatic Brain Disease Is Not Influenced by the Immunological Defense Mediated by CD57+ NK-Cells. International Journal of Surgical Oncology. 2011. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501875
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501875
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر