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Effects of Low-Intensity Laser Irradiation on Wound Healing in Diabetic Rats
المؤلفون المشاركون
Kang, Mei-ling
Chen, Hong-li
Ma, Hui
Liu, Timon Cheng-Yi
Li, Ying-xin
المصدر
International Journal of Photoenergy
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
The effects of low-intensity 630 nm semiconductor laser irradiation at 3.6 J/cm2 (LISL) on wound healing in diabetic rats were studied in this paper.
Methods.
36 diabetic rats with dorsal cutaneous excisional wounds were divided into three LISL groups and a control group randomly.
The three LISL groups were irradiated with LISL at 5, 10, and 20 mW/cm2 five times a week for two weeks, respectively.
The process of wound healing was assessed by assessing blood glucose, calculating percentage of wound closure, histopathological evaluation, and immunohistochemical quantification.
Results.
Blood glucose of all groups remained at similar levels throughout the experiment.
LISL could obviously promote wound contraction, fibroblasts proliferation, and collagen synthesis, alter bFGF and TGF-β1 expression, and reduce inflammatory reaction in the early and middle phases of chronic wound-healing process.
However, LISL could not shorten cicatrization time, and the treatment effects were not sensitive to illuminate parameters in the later phase of the experiment.
Conclusions.
LISL might have auxiliary effects in the early and middle phases of wound healing in STZ-induced diabetic rats, but the reciprocity rule might not hold.
The wound-healing process of early-phase diabetes rats shows typical characteristics of self-limited disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ma, Hui& Li, Ying-xin& Chen, Hong-li& Kang, Mei-ling& Liu, Timon Cheng-Yi. 2012. Effects of Low-Intensity Laser Irradiation on Wound Healing in Diabetic Rats. International Journal of Photoenergy،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502208
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ma, Hui…[et al.]. Effects of Low-Intensity Laser Irradiation on Wound Healing in Diabetic Rats. International Journal of Photoenergy No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-502208
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ma, Hui& Li, Ying-xin& Chen, Hong-li& Kang, Mei-ling& Liu, Timon Cheng-Yi. Effects of Low-Intensity Laser Irradiation on Wound Healing in Diabetic Rats. International Journal of Photoenergy. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502208
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-502208
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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