Human Sperm Cryopreservation : Update on Techniques, Effect on DNA Integrity, and Implications for ART

المؤلفون المشاركون

Di Santo, Marlea
Tarozzi, Nicoletta
Nadalini, Marco
Borini, Andrea

المصدر

Advances in Urology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-12-13

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الأمراض

الملخص EN

Cryopreservation of human spermatozoa—introduced in the 1960's—has been recognized as an efficient procedure for management of male fertility before therapy for malignant diseases, vasectomy or surgical infertility treatments, to store donor and partner spermatozoa before assisted reproduction treatments and to ensure the recovery of a small number of spermatozoa in severe male factor infertility.

Despite the usefulness of it, cryopreservation may lead to deleterious changes of sperm structure and function: while the effects of cryopreservation on cells are well documented, to date there is no agreement in the literature on whether or not cryopreservation affects sperm chromatin integrity or on the use of a unique and functional protocol for the freezing-thawing procedure.

Therefore, sperm cryopreservation is an important component of fertility management and much of its successful application seems to affect the reproductive outcome of assisted reproduction technologies (ART): appropriate use of cryoprotectants before and sperm selection technologies after cryopreservation seem to have the greatest impact on preventing DNA fragmentation, thus improving sperm cryosurvival rates.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Di Santo, Marlea& Tarozzi, Nicoletta& Nadalini, Marco& Borini, Andrea. 2011. Human Sperm Cryopreservation : Update on Techniques, Effect on DNA Integrity, and Implications for ART. Advances in Urology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-503661

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Di Santo, Marlea…[et al.]. Human Sperm Cryopreservation : Update on Techniques, Effect on DNA Integrity, and Implications for ART. Advances in Urology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-503661

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Di Santo, Marlea& Tarozzi, Nicoletta& Nadalini, Marco& Borini, Andrea. Human Sperm Cryopreservation : Update on Techniques, Effect on DNA Integrity, and Implications for ART. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-503661

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-503661