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Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine : A Voxel-Based Morphometric Study
المؤلفون المشاركون
Stip, Benjamin
Bentaleb, Lahcen Ait
Stip, Emmanuel
Luck, David
Letourneau, Genevieve
المصدر
Schizophrenia Research and Treatment
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-05-25
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Second-generation antipsychotics treatment is associated with weight gain and metabolic disturbances.
Although much research has been done on the topic, the precise mechanisms underlying such side effects are still not well understood.
Method.
We followed over 16 weeks a group of 17 schizophrenia patients who were treated with olanzapine and monitored biometric, clinical, and metabolic data, including ghrelin and leptin levels.
All patients had a structural cerebral magnetic resonance imaging examination during the first week of their followup and at the end of the study.
Results.
We found positive and negative significant correlations between grey matter volumes of several brain regions and variations of body weight as well as of ghrelin and leptin levels.
The right frontal operculum, bilateral precuneus, and bilateral hippocampal regions were found to be significantly associated with those changes.
Conclusion.
Our results suggest associations between brain structure and metabolic variations in schizophrenia patients taking olanzapine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Letourneau, Genevieve& Bentaleb, Lahcen Ait& Stip, Benjamin& Luck, David& Stip, Emmanuel. 2011. Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine : A Voxel-Based Morphometric Study. Schizophrenia Research and Treatment،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-504266
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Letourneau, Genevieve…[et al.]. Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine : A Voxel-Based Morphometric Study. Schizophrenia Research and Treatment No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-504266
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Letourneau, Genevieve& Bentaleb, Lahcen Ait& Stip, Benjamin& Luck, David& Stip, Emmanuel. Relationships between Brain Structure and Metabolic Changes in Schizophrenia Patients Treated with Olanzapine : A Voxel-Based Morphometric Study. Schizophrenia Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-504266
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-504266
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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