Effects of Dexmedetomidine-Fentanyl Infusion on Blood Pressure and Heart Rate during Cardiac Surgery in Children
المؤلفون المشاركون
Garcia, Luis Vicente
Vicente, Walter Villela de Andrade
Klamt, Jyrson Guilherme
Ferreira, Cesar Augusto
المصدر
Anesthesiology Research and Practice
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-08-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The purpose of this study was to access the effects of dexmedetomidine-fentanyl infusion on blood pressure (BP) and heart rate (HR) before surgical stimulation, on their changes to skin incision, and on isoflurane requirement during cardiac surgery in children.
Methods.
This study had a prospective, randomized, and open-label design.
Thirty-two children aged 1 month to 10 years undergoing surgery for repair congenital heart disease (CHD) with CPB were randomly allocated into two groups: group MDZ received midazolam 0.2 mg⋅kg−1⋅h−1 and group DEX received dexmedetomidine 1 μg⋅kg−1⋅h−1 during the first hour followed by half of these rates of infusions thereafter.
Both group received fentanyl 10 μg⋅kg−1, midazolam 0.2 mg⋅kg−1 and vecuronium 0.2 mg⋅kg−1 for induction.
These same doses of fentanyl and vecuronium were infused during the first hour then reduced to half.
The infusions started after induction and maintained until the end of surgery.
Isoflurane was given briefly to control hyperdynamic response to skin incision and sternotomy.
Results.
In both groups, systolic blood pressure (sBP) and heart rate (HR) decreased significantly after one hour of infusion of the anesthetic solutions, but there were significantly less increase in diastolic blood pressure, sBP, and HR, and less patients required isoflurane supplementation to skin incision in the patients of the DEX group.
Discussion.
Dexmedetomidine infusion without a bolus appears to be an effective adjunct to fentanyl anesthesia in control of hemodynamic responses to surgery for repair of CHD in children.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Klamt, Jyrson Guilherme& Vicente, Walter Villela de Andrade& Garcia, Luis Vicente& Ferreira, Cesar Augusto. 2010. Effects of Dexmedetomidine-Fentanyl Infusion on Blood Pressure and Heart Rate during Cardiac Surgery in Children. Anesthesiology Research and Practice،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-504792
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Klamt, Jyrson Guilherme…[et al.]. Effects of Dexmedetomidine-Fentanyl Infusion on Blood Pressure and Heart Rate during Cardiac Surgery in Children. Anesthesiology Research and Practice No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-504792
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Klamt, Jyrson Guilherme& Vicente, Walter Villela de Andrade& Garcia, Luis Vicente& Ferreira, Cesar Augusto. Effects of Dexmedetomidine-Fentanyl Infusion on Blood Pressure and Heart Rate during Cardiac Surgery in Children. Anesthesiology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-504792
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-504792
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر