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Strain Echocardiography in Early Detection of Doxorubicin-Induced Left Ventricular Dysfunction in Children with Acute Lymphoblastic Leukemia
المؤلفون المشاركون
Abd Rab Elrasoul Tolba, Osama
El-Sayed El-Hawary, Eslam
El-Shanshory, Mohammed Ramadan
Abd El-Aziz El-Shitany, Nagla
al-Biltagi, Mohammed
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-24
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
علم الصيدلة
الملخص EN
Objective.
To investigate the ability of two-dimensional longitudinal strain echocardiography (2DST), to detect the early doxorubicin cardiotoxicity.
Patients and Methods.
The study included 25 children with newly diagnosed acute lymphoblastic leukemia (ALL) aged 5–15 years and 30 healthy control children.
They had echocardiographic examination with conventional 2-dimensional (2D), pulsed tissue Doppler (PTD), and 2DST echocardiography before and within 1 week after doxorubicin treatment.
Results.
There was no significant difference in left ventricle (LV) systolic and diastolic functions measured by conventional 2-D and PTD echocardiography between patients and controls.
However, there was significant decrease in LV global and peak systolic strain detected by 2-DST echocardiography in study group than control.
After doxorubicin treatment, there was no significant difference in LV systolic and diastolic functions measured by conventional 2-D and PTD echocardiography than before treatment except for prolonged IVCT and IVRT, but LV global and peak systolic strain was significantly lower after treatment.
Conclusion.
2-D longitudinal strain echocardiography was more sensitive than conventional 2-D and PTD in detecting the early LV doxorubicin-induced cardiotoxicity in children with ALL.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Biltagi, Mohammed& Abd Rab Elrasoul Tolba, Osama& El-Shanshory, Mohammed Ramadan& Abd El-Aziz El-Shitany, Nagla& El-Sayed El-Hawary, Eslam. 2012. Strain Echocardiography in Early Detection of Doxorubicin-Induced Left Ventricular Dysfunction in Children with Acute Lymphoblastic Leukemia. ISRN Pediatrics،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504924
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Biltagi, Mohammed…[et al.]. Strain Echocardiography in Early Detection of Doxorubicin-Induced Left Ventricular Dysfunction in Children with Acute Lymphoblastic Leukemia. ISRN Pediatrics No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-504924
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Biltagi, Mohammed& Abd Rab Elrasoul Tolba, Osama& El-Shanshory, Mohammed Ramadan& Abd El-Aziz El-Shitany, Nagla& El-Sayed El-Hawary, Eslam. Strain Echocardiography in Early Detection of Doxorubicin-Induced Left Ventricular Dysfunction in Children with Acute Lymphoblastic Leukemia. ISRN Pediatrics. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504924
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-504924
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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