Prognostic Factors and Survival in Pediatric and Adolescent Liposarcoma
المؤلفون المشاركون
Singer, Samuel
La Quaglia, Michael P.
Stanelle, Eric J.
Meyers, Paul A.
Christison-Lagay, Emily R.
Antonescu, Cristina R.
Sidebotham, Emma L.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
Liposarcoma is extremely rare in the pediatric population.
To identify prognostic factors and determine treatment outcomes, we reviewed our institutional experience with pediatric liposarcoma.
Methods.
We retrospectively reviewed all pediatric patients (age <22 years) with confirmed liposarcoma treated at Memorial Sloan-Kettering Cancer Center.
Histologic subtype, tumor location, margin status, recurrence, and adjuvant therapy were analyzed and correlated with overall survival.
Results.
Thirty-four patients (56% male) with a median age of 18.1 years were identified.
Twenty-two (65%) had peripheral tumors and 12 (35%) had centrally located tumors.
Histologically, 29 (85%) tumors were low grade, and 5 (15%) were high grade pleomorphic.
Eleven (32%) had recurrent disease, 9 patients with central tumors and 2 patients with peripheral lesions.
Eight deaths occurred, all in patients with central disease.
Five-year overall survival was 78%, with a median follow-up time of 5.4 years (range, 0.3–30.3 years).
Tumor grade (P=.003), histologic subtype (P=.01), and primary location (P<.001) all correlated with survival, as did stage (P<.001) and margin status (P=.001).
Conclusions.
Central location of the primary tumor, high tumor grade, and positive surgical margins are strongly correlated with poor survival in pediatric patients with liposarcoma.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Stanelle, Eric J.& Christison-Lagay, Emily R.& Sidebotham, Emma L.& Singer, Samuel& Antonescu, Cristina R.& Meyers, Paul A.…[et al.]. 2012. Prognostic Factors and Survival in Pediatric and Adolescent Liposarcoma. Sarcoma،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-504961
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Stanelle, Eric J.…[et al.]. Prognostic Factors and Survival in Pediatric and Adolescent Liposarcoma. Sarcoma No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-504961
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Stanelle, Eric J.& Christison-Lagay, Emily R.& Sidebotham, Emma L.& Singer, Samuel& Antonescu, Cristina R.& Meyers, Paul A.…[et al.]. Prognostic Factors and Survival in Pediatric and Adolescent Liposarcoma. Sarcoma. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-504961
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-504961
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر