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Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1
المؤلفون المشاركون
Jiang, Jingfeng
Wang, Ling-Ling
Zhang, Jian-Bin
Xu, Bin
Wang, Gui-Ying
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
To compare the effects of moxibustion at two different temperatures (38°C and 46°C) on the blood cholesterol level in a mice model of acute hyperlipidemia, to detect the different expression levels of transient receptor potential vanilloid subfamily 1 (TRPV1) in the dorsal root ganglions of the wild mice, and to explore the correlation between TRPV1 and moxibustion’s cholesterol-lowering effects.
Method.
Two different mice models were used: C57BL/6J wild type (WT) and TRPV1 gene knockout (TRPV1−/−).
Each model was randomly divided into control group and model group with three subgroups after acute hyperlipidemia was established: model control group, 38°C moxibustion group, and 46°C moxibustion group.
The mice in 38°C group and 46°C group were subject to moxibustion.
After the therapy, the cholesterol concentration in serum was measured, and the expression of TRPV1 was quantified.
Results.
In WT mice, moxibustion caused a decrease in blood cholesterol level and upregulation of TRPV1 at the mRNA level, which was significantly greater in the 46°C group.
In contrast, in TRPV1−/− mice, the differences of cholesterol-lowering effects of moxibustion were lost.
Conclusions.
Temperature is one of the important factors affecting the effects of moxibustion, and the cholesterol -lowering effect of moxibustion is related to the activation of TRPV1.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Gui-Ying& Wang, Ling-Ling& Xu, Bin& Zhang, Jian-Bin& Jiang, Jingfeng. 2013. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Gui-Ying…[et al.]. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Gui-Ying& Wang, Ling-Ling& Xu, Bin& Zhang, Jian-Bin& Jiang, Jingfeng. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505046
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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