Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1
المؤلفون المشاركون
Jiang, Jingfeng
Wang, Ling-Ling
Zhang, Jian-Bin
Xu, Bin
Wang, Gui-Ying
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
To compare the effects of moxibustion at two different temperatures (38°C and 46°C) on the blood cholesterol level in a mice model of acute hyperlipidemia, to detect the different expression levels of transient receptor potential vanilloid subfamily 1 (TRPV1) in the dorsal root ganglions of the wild mice, and to explore the correlation between TRPV1 and moxibustion’s cholesterol-lowering effects.
Method.
Two different mice models were used: C57BL/6J wild type (WT) and TRPV1 gene knockout (TRPV1−/−).
Each model was randomly divided into control group and model group with three subgroups after acute hyperlipidemia was established: model control group, 38°C moxibustion group, and 46°C moxibustion group.
The mice in 38°C group and 46°C group were subject to moxibustion.
After the therapy, the cholesterol concentration in serum was measured, and the expression of TRPV1 was quantified.
Results.
In WT mice, moxibustion caused a decrease in blood cholesterol level and upregulation of TRPV1 at the mRNA level, which was significantly greater in the 46°C group.
In contrast, in TRPV1−/− mice, the differences of cholesterol-lowering effects of moxibustion were lost.
Conclusions.
Temperature is one of the important factors affecting the effects of moxibustion, and the cholesterol -lowering effect of moxibustion is related to the activation of TRPV1.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Gui-Ying& Wang, Ling-Ling& Xu, Bin& Zhang, Jian-Bin& Jiang, Jingfeng. 2013. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Gui-Ying…[et al.]. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Gui-Ying& Wang, Ling-Ling& Xu, Bin& Zhang, Jian-Bin& Jiang, Jingfeng. Effects of Moxibustion Temperature on Blood Cholesterol Level in a Mice Model of Acute Hyperlipidemia : Role of TRPV1. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505046
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505046
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر