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Oral HIV-Associated Kaposi Sarcoma : A Clinical Study from the Ga-Rankuwa Area, South Africa
المؤلفون المشاركون
Feller, Liviu
Pantanowitz, Liron
Khammissa, Razia A. G.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-12
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Kaposi sarcoma (KS) is one of the most common neoplasms diagnosed in HIV-seropositive subjects.
Oral involvement is frequent and is associated with a poor prognosis.
The aim of this study was to characterize the features of oral HIV-KS in patients from Ga-Rankuwa, South Africa.
Methods.
All cases with confirmed oral HIV-KS treated at the oral medicine clinic in Ga-Rankuwa from 2004 to 2010 were included in this retrospective study.
Differences between males and females with oral HIV-KS in relation to HIV infection status, to oral KS presentation and to survival rates were statistically analysed.
Results.
Twenty (54%) of the 37 patients in the study were females and 17 (46%) were males.
In 21 patients (57%), the initial presentation of HIV-KS was in the mouth.
Other than the fact that females presented with larger (≥10 mm) oral KS lesions (P=0.0004), there were no statistically significant gender differences.
Significantly more patients presented with multiple oral HIV-KS lesions than with single lesions (P=0.0003).
Nine patients (24%) developed concomitant facial lymphoedema, and these patients had a significantly lower CD4+ T-cell count (28 cells/mm3) compared to the rest of the group (130 cells/mm3) (P=0.01).
The average CD4+ T-cell count of the patients who died (64 cells/mm3) was significantly lower (P=0.0004), there were no statistically significant gender differences.
Significantly more patients presented with multiple oral HIV-KS lesions than with single lesions (P=0.016) at the time of oral-KS presentation than of those who survived (166 cells/mm3).
Conclusions: In Ga-Rankuwa, South Africa where HIV-KS is prevalent, oral KS affects similarly males and females.
A low CD4+ T-cell count at the time of oral HIV-KS diagnosis and the development of facial lymphoedema during the course of HIV-KS disease portends a poor prognosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khammissa, Razia A. G.& Pantanowitz, Liron& Feller, Liviu. 2012. Oral HIV-Associated Kaposi Sarcoma : A Clinical Study from the Ga-Rankuwa Area, South Africa. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-505183
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khammissa, Razia A. G.…[et al.]. Oral HIV-Associated Kaposi Sarcoma : A Clinical Study from the Ga-Rankuwa Area, South Africa. AIDS Research and Treatment No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-505183
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khammissa, Razia A. G.& Pantanowitz, Liron& Feller, Liviu. Oral HIV-Associated Kaposi Sarcoma : A Clinical Study from the Ga-Rankuwa Area, South Africa. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-505183
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505183
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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