Small Cell Lung Cancer Presenting as Severe Thrombocytopenia and Refractory Hypokalemia
المؤلفون المشاركون
LePar, Felice
Hughes, Lesley
Mandaliya, Rohan
Auerbach, Herbert
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-15
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
A 70-year-old female with a history of mild cirrhosis was referred by her primary care provider for a platelet count of 36,000/μL which had dropped from 47,000/μL in a week along with mild pain in extremities.
Serum potassium was low (2.9 mEq/L) in spite of the patient being recently started on potassium supplement on outpatient for hypokalemia.
Initially thrombocytopenia was attributed to cirrhosis.
However, platelet counts continued to drop to a nadir of 9000/μL in spite of several platelet transfusions.
Hypokalemia was refractory to potassium supplements.
Subsequent bone marrow biopsy revealed extensive marrow necrosis with a focus of small cell tumor cells of pulmonary origin.
CT scan of the chest showed a spiculated left lung mass.
The ACTH level was high, with normal rennin and aldosterone levels.
The patient likely had ectopic ACTH syndrome from small cell lung cancer.
She died within few days of diagnosis.
Severe thrombocytopenia and refractory hypokalemia can rarely be initial presentations of small cell lung cancer.
Thrombocytopenia should prompt an evaluation for bone marrow metastases and a search for undiagnosed systemic malignancy.
In severe cases of metastases, bone marrow necrosis can be present.
Refractory hypokalemia can be the sole presentation of ectopic ACTH production.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mandaliya, Rohan& Hughes, Lesley& Auerbach, Herbert& LePar, Felice. 2014. Small Cell Lung Cancer Presenting as Severe Thrombocytopenia and Refractory Hypokalemia. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-505328
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mandaliya, Rohan…[et al.]. Small Cell Lung Cancer Presenting as Severe Thrombocytopenia and Refractory Hypokalemia. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-505328
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mandaliya, Rohan& Hughes, Lesley& Auerbach, Herbert& LePar, Felice. Small Cell Lung Cancer Presenting as Severe Thrombocytopenia and Refractory Hypokalemia. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-505328
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505328
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر