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Prooxidant Effects of Verbascoside, a Bioactive Compound from Olive Oil Mill Wastewater, on In Vitro Developmental Potential of Ovine Prepubertal Oocytes and BioenergeticOxidative Stress Parameters of Fresh and Vitrified Oocytes
المؤلفون المشاركون
Bogliolo, L.
Ferruzzi, M. G.
Sardanelli, A. M.
Ariu, F.
Russo, R.
Martino, Nicola Antonio
Cardinali, Angela
Filioli Uranio, M.
Minervini, F.
Dell'Aquila, M. E.
Linsalata, V.
Amati, F.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-25
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Verbascoside (VB) is a bioactive polyphenol from olive oil mill wastewater with known antioxidant activity.
Oxidative stress is an emerging problem in assisted reproductive technology (ART).
Juvenile ART is a promising topic because, in farm animals, it reduces the generation gap and, in human reproductive medicine, it helps to overcome premature ovarian failure.
The aim of this study was to test the effects of VB on the developmental competence of ovine prepubertal oocytes and the bioenergetic/oxidative stress status of fresh and vitrified oocytes.
In fresh oocytes, VB exerted prooxidant short-term effects, that is, catalase activity increase and uncoupled increases of mitochondria and reactive oxygen species (ROS) fluorescence signals, and long-term effects, that is, reduced blastocyst formation rate.
In vitrified oocytes, VB increased ROS levels.
Prooxidant VB effects in ovine prepubertal oocytes could be related to higher VB accumulation, which was found as almost one thousand times higher than that reported in other cell systems in previous studies.
Also, long exposure times of oocytes to VB, throughout the duration of in vitro maturation culture, may have contributed to significant increase of oocyte oxidation.
Further studies are needed to identify lower concentrations and/or shorter exposure times to figure out VB antioxidant effects in juvenile ARTs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dell'Aquila, M. E.& Bogliolo, L.& Russo, R.& Martino, Nicola Antonio& Filioli Uranio, M.& Ariu, F.…[et al.]. 2014. Prooxidant Effects of Verbascoside, a Bioactive Compound from Olive Oil Mill Wastewater, on In Vitro Developmental Potential of Ovine Prepubertal Oocytes and BioenergeticOxidative Stress Parameters of Fresh and Vitrified Oocytes. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-505542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dell'Aquila, M. E.…[et al.]. Prooxidant Effects of Verbascoside, a Bioactive Compound from Olive Oil Mill Wastewater, on In Vitro Developmental Potential of Ovine Prepubertal Oocytes and BioenergeticOxidative Stress Parameters of Fresh and Vitrified Oocytes. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-505542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dell'Aquila, M. E.& Bogliolo, L.& Russo, R.& Martino, Nicola Antonio& Filioli Uranio, M.& Ariu, F.…[et al.]. Prooxidant Effects of Verbascoside, a Bioactive Compound from Olive Oil Mill Wastewater, on In Vitro Developmental Potential of Ovine Prepubertal Oocytes and BioenergeticOxidative Stress Parameters of Fresh and Vitrified Oocytes. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-505542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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